Activated MLKL attenuates autophagy following its translocation to intracellular membranes.

Frank, Daniel; Vaux, David L; Murphy, James M; Vince, James E; Lindqvist, Lisa M

Frank, Daniel; Vaux, David L; Murphy, James M; Vince, James E; Lindqvist, Lisa M.

Afiliação

Frank D; Cell Signalling and Cell Death Division, The Walter and Eliza Hall Institute of Medical Research, 1G Royal Parade, Melbourne, Victoria 3052, Australia.
Vaux DL; Department of Medical Biology, The University of Melbourne, Parkville, Victoria 3050, Australia.
Murphy JM; Cell Signalling and Cell Death Division, The Walter and Eliza Hall Institute of Medical Research, 1G Royal Parade, Melbourne, Victoria 3052, Australia.
Vince JE; Department of Medical Biology, The University of Melbourne, Parkville, Victoria 3050, Australia.
Lindqvist LM; Cell Signalling and Cell Death Division, The Walter and Eliza Hall Institute of Medical Research, 1G Royal Parade, Melbourne, Victoria 3052, Australia.

J Cell Sci ; 132(5)2019 02 28.

Article em En | MEDLINE | ID: mdl-30709919

Assuntos

Autofagossomos/metabolismo; Neoplasias Colorretais/metabolismo; Derme/patologia; Fibroblastos/metabolismo; Membranas Intracelulares/metabolismo; Proteínas Quinases/metabolismo; Animais; Autofagia; Repetições Palindrômicas Curtas Agrupadas e Regularmente Espaçadas; Neoplasias Colorretais/patologia; Fibroblastos/patologia; Técnicas de Inativação de Genes; Células HT29; Humanos; Camundongos; Camundongos Endogâmicos C57BL; Camundongos Knockout; Necroptose; Proteínas Quinases/genética; Transporte Proteico

Palavras-chave

Autophagy; LC3; MLKL; Necroptosis

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Proteínas Quinases / Neoplasias Colorretais / Derme / Fibroblastos / Autofagossomos / Membranas Intracelulares Limite: Animals / Humans Idioma: En Ano de publicação: 2019 Tipo de documento: Article

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