Abinukitrine A, a unique 17,18-cyclolanostane triterpenoid from Abies nukiangensis.

Li, Yong-Li; Xue, Li-Jun; Li, Jie; Chen, Li-Ming; Wu, Jian-Jun; Xu, Zhuo-Ni; Chen, Ying; Tian, Yu-Ping; Yang, Xian-Wen

Li, Yong-Li; Xue, Li-Jun; Li, Jie; Chen, Li-Ming; Wu, Jian-Jun; Xu, Zhuo-Ni; Chen, Ying; Tian, Yu-Ping; Yang, Xian-Wen.

Afiliação

Li YL; Physical and Chemical Analysis laboratory, Division of Material Science & Quality Test, Shanghai Institute of Measurement and Testing Technology, 1500 Zhangheng Road, Shanghai 201203, China. liyl@simt.com.cn.

Org Biomol Chem ; 17(8): 2107-2109, 2019 02 20.

Article em En | MEDLINE | ID: mdl-30720826

ABSTRACT

ABSTRACT

Abinukitrine A (1), a novel triterpenoid, was isolated from Abies nukiangensis. Comprehensive spectroscopic analysis revealed that 1 is the first example of 17,18-cyclolanostane bearing a unique 6/6/6/5/3 ring system. Its absolute configuration was unequivocally assigned by Cu-Kα X-ray single-crystallography. Compound 1 showed a potent anti-hepatitis C virus (HCV) effect.

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Texto completo: 1 Base de dados: MEDLINE Idioma: En Ano de publicação: 2019 Tipo de documento: Article

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Texto completo: 1 Base de dados: MEDLINE Idioma: En Ano de publicação: 2019 Tipo de documento: Article