The Impact of the Right Coronary Artery Geometric Parameters on Hemodynamic Performance.
Cardiovasc Eng Technol
; 10(2): 257-270, 2019 06.
Article
em En
| MEDLINE
| ID: mdl-30725435
ABSTRACT
PURPOSE:
Coronary artery geometry can have a significant impact in the hemodynamic behavior of coronary blood flow, influencing atherosclerotic plaque formation. The present work focuses on, through a statistical study, the connection between several geometric parameters of the right coronary artery-ostium cross-sectional area, angles between the common trunk and the side-branches, tortuosity, curvature and cross-sectional area in each side-branch-and their influence on hemodynamic descriptors. Parameters such as low wall shear stress and local disturbed flow, which are associated with atherosclerosis formation, were analysed.METHODS:
Computed tomography images of ten healthy individuals were selected to reconstruct in vivo three-dimensional models of right coronary arteries. Blood flow was simulated through a compliant model with realistic boundary conditions. Calculated hemodynamic descriptors values were correlated with the geometric parameters using the Pearson correlation coefficient (r) and the p value.RESULTS:
The strongest correlations were found in the middle and distal segments of the right coronary artery. A decrease in the ostium area promotes a decrease in the WSS magnitude from the proximal to the distal segment (r = 0.82). Very strong correlations (r > 0.90) were achieved between geometric parameters (cross-sectional area, angle, tortuosity) of the right-ventricular branch and the wall shear stress magnitude in the middle and distal segments.CONCLUSIONS:
Low values of tortuosity, smaller cross-sectional area and higher angle of the right-ventricular branch leads to a hemodynamic behavior more propitious to atherosclerosis formation, within the study cases. The right-ventricular branch seems to have the highest influence in the hemodynamic behavior of the right coronary artery.Palavras-chave
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Angiografia Coronária
/
Circulação Coronária
/
Vasos Coronários
/
Modelagem Computacional Específica para o Paciente
/
Angiografia por Tomografia Computadorizada
/
Hemodinâmica
/
Modelos Cardiovasculares
Tipo de estudo:
Prognostic_studies
Limite:
Adult
/
Humans
/
Male
Idioma:
En
Ano de publicação:
2019
Tipo de documento:
Article