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Loss of TET proteins in regulatory T cells promotes abnormal proliferation, Foxp3 destabilization and IL-17 expression.
Nakatsukasa, Hiroko; Oda, Mayumi; Yin, Jinghua; Chikuma, Shunsuke; Ito, Minako; Koga-Iizuka, Mana; Someya, Kazue; Kitagawa, Yohko; Ohkura, Naganari; Sakaguchi, Shimon; Koya, Ikuko; Sanosaka, Tsukasa; Kohyama, Jun; Tsukada, Yu-Ichi; Yamanaka, Soichiro; Takamura-Enya, Takeji; Lu, Qianjin; Yoshimura, Akihiko.
Afiliação
  • Nakatsukasa H; Department of Microbiology and Immunology.
  • Oda M; Department of Systems Medicine, Keio University School of Medicine, 35 Shinanomachi, Shinjuku-ku, Tokyo 160-8582, Japan.
  • Yin J; Department of Dermatology, Second Xiangya Hospital, Central South University, Hunan Key Laboratory of Medical Epigenomics, Changsha, Hunan 410011, China.
  • Chikuma S; Department of Microbiology and Immunology.
  • Ito M; Department of Microbiology and Immunology.
  • Koga-Iizuka M; Department of Microbiology and Immunology.
  • Someya K; Department of Microbiology and Immunology.
  • Kitagawa Y; Department of Experimental Immunology, Immunology Frontier Research Center, Osaka University, 3-1 Yamada-oka, Suita 565-0871, Japan.
  • Ohkura N; Department of Experimental Immunology, Immunology Frontier Research Center, Osaka University, 3-1 Yamada-oka, Suita 565-0871, Japan.
  • Sakaguchi S; Department of Experimental Immunology, Immunology Frontier Research Center, Osaka University, 3-1 Yamada-oka, Suita 565-0871, Japan.
  • Koya I; Department of Physiology, Keio University School of Medicine, 35 Shinanomachi, Shinjuku-ku, Tokyo 160-8582, Japan.
  • Sanosaka T; Department of Physiology, Keio University School of Medicine, 35 Shinanomachi, Shinjuku-ku, Tokyo 160-8582, Japan.
  • Kohyama J; Department of Physiology, Keio University School of Medicine, 35 Shinanomachi, Shinjuku-ku, Tokyo 160-8582, Japan.
  • Tsukada YI; Advanced Biological Information Research Division, INAMORI Frontier Research Center, Kyushu University, Fukuoka, Fukuoka 819-0395, Japan.
  • Yamanaka S; Department of Molecular Biology, Keio University School of Medicine, 35 Shinanomachi, Shinjuku-ku, Tokyo 160-8582, Japan.
  • Takamura-Enya T; Department of Applied Chemistry, Kanagawa Institute of Technology, Shimo-Ogino 1030, Atsugi-shi 243-0292, Japan.
  • Lu Q; Department of Dermatology, Second Xiangya Hospital, Central South University, Hunan Key Laboratory of Medical Epigenomics, Changsha, Hunan 410011, China.
  • Yoshimura A; Department of Microbiology and Immunology.
Int Immunol ; 31(5): 335-347, 2019 04 26.
Article em En | MEDLINE | ID: mdl-30726915
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Proteínas Proto-Oncogênicas / Linfócitos T Reguladores / Interleucina-17 / Dioxigenases / Proteínas de Ligação a DNA / Fatores de Transcrição Forkhead Tipo de estudo: Prognostic_studies Limite: Animals Idioma: En Ano de publicação: 2019 Tipo de documento: Article
Texto completo
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Proteínas Proto-Oncogênicas / Linfócitos T Reguladores / Interleucina-17 / Dioxigenases / Proteínas de Ligação a DNA / Fatores de Transcrição Forkhead Tipo de estudo: Prognostic_studies Limite: Animals Idioma: En Ano de publicação: 2019 Tipo de documento: Article