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Design, synthesis and evaluation of a series of 5-methoxy-2,3-naphthalimide derivatives as AcrB inhibitors for the reversal of bacterial resistance.
Jin, Chaobin; Alenazy, Rawaf; Wang, Yinhu; Mowla, Rumana; Qin, Yinhui; Tan, Jin Quan Eugene; Modi, Natansh Deepak; Gu, Xinjie; Polyak, Steven W; Venter, Henrietta; Ma, Shutao.
Afiliação
  • Jin C; Department of Medicinal Chemistry, Key Laboratory of Chemical Biology (Ministry of Education), School of Pharmaceutical Sciences, Shandong University, 44 West Culture Road, Jinan 250012, China; Department of Medical Laboratory, College of Applied Medical Sciences - Shaqra, Shaqra University, 11961,
  • Alenazy R; School of Pharmacy and Medical Sciences, University of South Australia, SA 5000, Australia; Department of Medical Laboratory, College of Applied Medical Sciences - Shaqra, Shaqra University, 11961, Saudi Arabia.
  • Wang Y; Department of Medicinal Chemistry, Key Laboratory of Chemical Biology (Ministry of Education), School of Pharmaceutical Sciences, Shandong University, 44 West Culture Road, Jinan 250012, China.
  • Mowla R; School of Pharmacy and Medical Sciences, University of South Australia, SA 5000, Australia.
  • Qin Y; Department of Medicinal Chemistry, Key Laboratory of Chemical Biology (Ministry of Education), School of Pharmaceutical Sciences, Shandong University, 44 West Culture Road, Jinan 250012, China.
  • Tan JQE; School of Pharmacy and Medical Sciences, University of South Australia, SA 5000, Australia.
  • Modi ND; School of Pharmacy and Medical Sciences, University of South Australia, SA 5000, Australia.
  • Gu X; Department of Medicinal Chemistry, Key Laboratory of Chemical Biology (Ministry of Education), School of Pharmaceutical Sciences, Shandong University, 44 West Culture Road, Jinan 250012, China.
  • Polyak SW; School of Pharmacy and Medical Sciences, University of South Australia, SA 5000, Australia.
  • Venter H; School of Pharmacy and Medical Sciences, University of South Australia, SA 5000, Australia. Electronic address: rietie.venter@unisa.edu.au.
  • Ma S; Department of Medicinal Chemistry, Key Laboratory of Chemical Biology (Ministry of Education), School of Pharmaceutical Sciences, Shandong University, 44 West Culture Road, Jinan 250012, China. Electronic address: mashutao@sdu.edu.cn.
Bioorg Med Chem Lett ; 29(7): 882-889, 2019 04 01.
Article em En | MEDLINE | ID: mdl-30755336
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Proteínas de Escherichia coli / Proteínas Associadas à Resistência a Múltiplos Medicamentos / Farmacorresistência Bacteriana / Escherichia coli / Naftalimidas / Antibacterianos Idioma: En Ano de publicação: 2019 Tipo de documento: Article
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Proteínas de Escherichia coli / Proteínas Associadas à Resistência a Múltiplos Medicamentos / Farmacorresistência Bacteriana / Escherichia coli / Naftalimidas / Antibacterianos Idioma: En Ano de publicação: 2019 Tipo de documento: Article