Sequence selection by FitSS4ASR alleviates ancestral sequence reconstruction as exemplified for geranylgeranylglyceryl phosphate synthase.

Straub, Kristina; Linde, Mona; Kropp, Cosimo; Blanquart, Samuel; Babinger, Patrick; Merkl, Rainer

Straub, Kristina; Linde, Mona; Kropp, Cosimo; Blanquart, Samuel; Babinger, Patrick; Merkl, Rainer.

Afiliação

Straub K; Institute of Biophysics and Physical Biochemistry, University of Regensburg, Universitätsstraße 31, D-93040 Regensburg, Germany.
Linde M; Institute of Biophysics and Physical Biochemistry, University of Regensburg, Universitätsstraße 31, D-93040 Regensburg, Germany.
Kropp C; Institute of Biophysics and Physical Biochemistry, University of Regensburg, Universitätsstraße 31, D-93040 Regensburg, Germany.
Blanquart S; University of Rennes, Inria, CNRS, IRISA, F-35000 Rennes, France.
Babinger P; Institute of Biophysics and Physical Biochemistry, University of Regensburg, Universitätsstraße 31, D-93040 Regensburg, Germany.
Merkl R; Institute of Biophysics and Physical Biochemistry, University of Regensburg, Universitätsstraße 31, D-93040 Regensburg, Germany.

Biol Chem ; 400(3): 367-381, 2019 02 25.

Article em En | MEDLINE | ID: mdl-30763032

Assuntos

Alquil e Aril Transferases/genética; Software; Alquil e Aril Transferases/isolamento & purificação; Alquil e Aril Transferases/metabolismo; Sequência de Aminoácidos; Clonagem Molecular; Evolução Molecular; Filogenia; Engenharia de Proteínas; Fatores de Tempo

Palavras-chave

common ancestors; oligomerization; protein design; protein evolution; sequence space

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Software / Alquil e Aril Transferases Idioma: En Ano de publicação: 2019 Tipo de documento: Article

Texto completo

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PubMed Links

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Software / Alquil e Aril Transferases Idioma: En Ano de publicação: 2019 Tipo de documento: Article