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4,6-Substituted-1H-Indazoles as potent IDO1/TDO dual inhibitors.
Yang, Lingling; Chen, Yang; He, Junlin; Njoya, Emmanuel Mfotie; Chen, Jianjun; Liu, Siyan; Xie, Congqiang; Huang, Wenze; Wang, Fei; Wang, Zhouyu; Li, Yuzhi; Qian, Shan.
Afiliação
  • Yang L; Department of Pharmaceutical Engineering, School of Food and Bioengineering, Xihua University, Chengdu 610039, China.
  • Chen Y; Department of Pharmaceutical Engineering, School of Food and Bioengineering, Xihua University, Chengdu 610039, China.
  • He J; Key Laboratory of Systematic Research, Development and Utilization of Chinese Medicine Resources, Pharmacy College, Chengdu University of Traditional Chinese Medicine, Chengdu 610091, China.
  • Njoya EM; Key Laboratory of Natural Medicine and Clinical Translation, Chengdu Institute of Biology, Chinese Academy of Sciences, Chengdu 610041, China.
  • Chen J; Department of Pharmaceutical Engineering, School of Food and Bioengineering, Xihua University, Chengdu 610039, China.
  • Liu S; Department of Pharmaceutical Engineering, School of Food and Bioengineering, Xihua University, Chengdu 610039, China.
  • Xie C; Department of Pharmaceutical Engineering, School of Food and Bioengineering, Xihua University, Chengdu 610039, China.
  • Huang W; Department of Pharmaceutical Engineering, School of Food and Bioengineering, Xihua University, Chengdu 610039, China.
  • Wang F; Key Laboratory of Natural Medicine and Clinical Translation, Chengdu Institute of Biology, Chinese Academy of Sciences, Chengdu 610041, China.
  • Wang Z; Department of Pharmaceutical Engineering, School of Food and Bioengineering, Xihua University, Chengdu 610039, China. Electronic address: zhouyuwang77@gmail.com.
  • Li Y; Key Laboratory of Systematic Research, Development and Utilization of Chinese Medicine Resources, Pharmacy College, Chengdu University of Traditional Chinese Medicine, Chengdu 610091, China. Electronic address: liyuzhi5654@163.com.
  • Qian S; Department of Pharmaceutical Engineering, School of Food and Bioengineering, Xihua University, Chengdu 610039, China. Electronic address: qians33@163.com.
Bioorg Med Chem ; 27(6): 1087-1098, 2019 03 15.
Article em En | MEDLINE | ID: mdl-30773421
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Triptofano Oxigenase / Inibidores Enzimáticos / Indolamina-Pirrol 2,3,-Dioxigenase / Indazóis Tipo de estudo: Prognostic_studies Limite: Animals / Humans Idioma: En Ano de publicação: 2019 Tipo de documento: Article
Texto completo
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Triptofano Oxigenase / Inibidores Enzimáticos / Indolamina-Pirrol 2,3,-Dioxigenase / Indazóis Tipo de estudo: Prognostic_studies Limite: Animals / Humans Idioma: En Ano de publicação: 2019 Tipo de documento: Article