Upregulation of miR-146a-5p is associated with increased proliferation and migration of vascular smooth muscle cells in aortic dissection.

Xue, Ling; Luo, Songyuan; Ding, Huanyu; Liu, Yuan; Huang, Wenhui; Fan, Xiaoping; Wu, Min; Jian, Xuhua; Huang, Cheng; Luo, Jianfang; Fan, Ruixin

Xue, Ling; Luo, Songyuan; Ding, Huanyu; Liu, Yuan; Huang, Wenhui; Fan, Xiaoping; Wu, Min; Jian, Xuhua; Huang, Cheng; Luo, Jianfang; Fan, Ruixin.

Afiliação

Xue L; Guangdong Cardiovascular Institute, Guangdong Provincial People' Hospital, Guangdong Academy of Medical Sciences, Guangdong, Guangzhou, China.
Luo S; Guangdong Cardiovascular Institute, Guangdong Provincial People' Hospital, Guangdong Academy of Medical Sciences, Guangdong, Guangzhou, China.
Ding H; Guangdong Cardiovascular Institute, Guangdong Provincial People' Hospital, Guangdong Academy of Medical Sciences, Guangdong, Guangzhou, China.
Liu Y; Guangdong Cardiovascular Institute, Guangdong Provincial People' Hospital, Guangdong Academy of Medical Sciences, Guangdong, Guangzhou, China.
Huang W; Guangdong Cardiovascular Institute, Guangdong Provincial People' Hospital, Guangdong Academy of Medical Sciences, Guangdong, Guangzhou, China.
Fan X; Guangdong Cardiovascular Institute, Guangdong Provincial People' Hospital, Guangdong Academy of Medical Sciences, Guangdong, Guangzhou, China.
Wu M; Guangdong Cardiovascular Institute, Guangdong Provincial People' Hospital, Guangdong Academy of Medical Sciences, Guangdong, Guangzhou, China.
Jian X; Guangdong Cardiovascular Institute, Guangdong Provincial People' Hospital, Guangdong Academy of Medical Sciences, Guangdong, Guangzhou, China.
Huang C; Guangdong Cardiovascular Institute, Guangdong Provincial People' Hospital, Guangdong Academy of Medical Sciences, Guangdong, Guangzhou, China.
Luo J; Guangdong Cardiovascular Institute, Guangdong Provincial People' Hospital, Guangdong Academy of Medical Sciences, Guangdong, Guangzhou, China.
Fan R; Guangdong Cardiovascular Institute, Guangdong Provincial People' Hospital, Guangdong Academy of Medical Sciences, Guangdong, Guangzhou, China.

J Clin Lab Anal ; 33(4): e22843, 2019 May.

Article em En | MEDLINE | ID: mdl-30779466

Assuntos

Aneurisma da Aorta Torácica/patologia; Dissecção Aórtica/patologia; MicroRNAs/genética; Músculo Liso Vascular/patologia; Proteína Smad4/genética; Adulto; Dissecção Aórtica/genética; Aneurisma da Aorta Torácica/genética; Estudos de Casos e Controles; Movimento Celular/genética; Proliferação de Células/genética; Ácidos Nucleicos Livres/sangue; Células Cultivadas; Feminino; Regulação da Expressão Gênica; Humanos; Masculino; MicroRNAs/sangue; Pessoa de Meia-Idade; Proteína Smad4/metabolismo; Regulação para Cima

Palavras-chave

SMAD4; aortic dissection; miR-146a-5p; migration; proliferation; vascular smooth muscle cell

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Aneurisma da Aorta Torácica / MicroRNAs / Proteína Smad4 / Dissecção Aórtica / Músculo Liso Vascular Tipo de estudo: Observational_studies / Risk_factors_studies Limite: Adult / Female / Humans / Male / Middle aged Idioma: En Ano de publicação: 2019 Tipo de documento: Article

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