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Blood-Derived DNA Methylation Signatures of Crohn's Disease and Severity of Intestinal Inflammation.
Somineni, Hari K; Venkateswaran, Suresh; Kilaru, Varun; Marigorta, Urko M; Mo, Angela; Okou, David T; Kellermayer, Richard; Mondal, Kajari; Cobb, Dawayland; Walters, Thomas D; Griffiths, Anne; Noe, Joshua D; Crandall, Wallace V; Rosh, Joel R; Mack, David R; Heyman, Melvin B; Baker, Susan S; Stephens, Michael C; Baldassano, Robert N; Markowitz, James F; Dubinsky, Marla C; Cho, Judy; Hyams, Jeffrey S; Denson, Lee A; Gibson, Greg; Cutler, David J; Conneely, Karen N; Smith, Alicia K; Kugathasan, Subra.
Afiliação
  • Somineni HK; Genetics and Molecular Biology Program, Emory University, Atlanta, Georgia; Division of Pediatric Gastroenterology, Department of Pediatrics, Emory University School of Medicine and Children's Healthcare of Atlanta, Atlanta, Georgia.
  • Venkateswaran S; Division of Pediatric Gastroenterology, Department of Pediatrics, Emory University School of Medicine and Children's Healthcare of Atlanta, Atlanta, Georgia.
  • Kilaru V; Department of Gynecology and Obstetrics, Emory University School of Medicine, Atlanta, Georgia.
  • Marigorta UM; Center for Integrative Genomics, Georgia Institute of Technology, Atlanta, Georgia.
  • Mo A; Center for Integrative Genomics, Georgia Institute of Technology, Atlanta, Georgia.
  • Okou DT; Division of Pediatric Gastroenterology, Department of Pediatrics, Emory University School of Medicine and Children's Healthcare of Atlanta, Atlanta, Georgia.
  • Kellermayer R; Section of Pediatric Gastroenterology, Baylor College of Medicine, Texas Children's Hospital, Houston, Texas.
  • Mondal K; Division of Pediatric Gastroenterology, Department of Pediatrics, Emory University School of Medicine and Children's Healthcare of Atlanta, Atlanta, Georgia.
  • Cobb D; Department of Gynecology and Obstetrics, Emory University School of Medicine, Atlanta, Georgia.
  • Walters TD; Division of Pediatric Gastroenterology, Hepatology and Nutrition, Department of Pediatrics, The Hospital for Sick Children, University of Toronto, Toronto, Ontario, Canada.
  • Griffiths A; Division of Pediatric Gastroenterology, Hepatology and Nutrition, Department of Pediatrics, The Hospital for Sick Children, University of Toronto, Toronto, Ontario, Canada.
  • Noe JD; Department of Pediatric Gastroenterology, Hepatology and Nutrition, Medical College of Wisconsin, Milwaukee, Wisconsin.
  • Crandall WV; Division of Pediatric Gastroenterology, Nationwide Children's Hospital, Ohio State University College of Medicine, Columbus, Ohio.
  • Rosh JR; Department of Pediatrics, Goryeb Children's Hospital, Morristown, New Jersey.
  • Mack DR; Department of Pediatrics, Children's Hospital of Eastern Ontario IBD Centre and University of Ottawa, Ottawa, Ontario, Canada.
  • Heyman MB; Department of Pediatrics, University of California, San Francisco, San Francisco, California.
  • Baker SS; Department of Digestive Diseases and Nutrition Center, University at Buffalo, Buffalo, New York.
  • Stephens MC; Department of Pediatric Gastroenterology, Mayo Clinic, Rochester, Minnesota.
  • Baldassano RN; Department of Pediatrics, University of Pennsylvania, Philadelphia, Pennsylvania.
  • Markowitz JF; Department of Pediatrics, Northwell Health, New York, New York.
  • Dubinsky MC; Department of Pediatrics, Mount Sinai Hospital, New York, New York.
  • Cho J; Department of Pediatrics, Mount Sinai Hospital, New York, New York.
  • Hyams JS; Division of Digestive Diseases, Hepatology, and Nutrition, Connecticut Children's Medical Center, Hartford, Connecticut.
  • Denson LA; Division of Pediatric Gastroenterology, Hepatology, and Nutrition, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio.
  • Gibson G; Center for Integrative Genomics, Georgia Institute of Technology, Atlanta, Georgia.
  • Cutler DJ; Department of Human Genetics, Emory University, Atlanta, Georgia.
  • Conneely KN; Genetics and Molecular Biology Program, Emory University, Atlanta, Georgia; Department of Human Genetics, Emory University, Atlanta, Georgia.
  • Smith AK; Genetics and Molecular Biology Program, Emory University, Atlanta, Georgia; Department of Gynecology and Obstetrics, Emory University School of Medicine, Atlanta, Georgia; Department of Psychiatry and Behavioral Sciences, Emory University, Atlanta, Georgia.
  • Kugathasan S; Genetics and Molecular Biology Program, Emory University, Atlanta, Georgia; Division of Pediatric Gastroenterology, Department of Pediatrics, Emory University School of Medicine and Children's Healthcare of Atlanta, Atlanta, Georgia; Department of Human Genetics, Emory University, Atlanta, Georgia.
Gastroenterology ; 156(8): 2254-2265.e3, 2019 06.
Article em En | MEDLINE | ID: mdl-30779925
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Doença de Crohn / Regulação da Expressão Gênica / Metilação de DNA / Estudo de Associação Genômica Ampla / Análise da Randomização Mendeliana Tipo de estudo: Clinical_trials / Etiology_studies / Observational_studies / Prognostic_studies / Risk_factors_studies Limite: Adolescent / Child / Child, preschool / Female / Humans / Infant / Male País como assunto: America do norte Idioma: En Ano de publicação: 2019 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Doença de Crohn / Regulação da Expressão Gênica / Metilação de DNA / Estudo de Associação Genômica Ampla / Análise da Randomização Mendeliana Tipo de estudo: Clinical_trials / Etiology_studies / Observational_studies / Prognostic_studies / Risk_factors_studies Limite: Adolescent / Child / Child, preschool / Female / Humans / Infant / Male País como assunto: America do norte Idioma: En Ano de publicação: 2019 Tipo de documento: Article