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Discovery of ((1,2,4-oxadiazol-5-yl)pyrrolidin-3-yl)ureidyl derivatives as selective non-steroidal agonists of the G-protein coupled bile acid receptor-1.
Di Leva, Francesco Saverio; Festa, Carmen; Carino, Adriana; De Marino, Simona; Marchianò, Silvia; Di Marino, Daniele; Finamore, Claudia; Monti, Maria Chiara; Zampella, Angela; Fiorucci, Stefano; Limongelli, Vittorio.
Afiliação
  • Di Leva FS; Department of Pharmacy, University of Naples "Federico II", via D. Montesano 49, 80131, Naples, Italy.
  • Festa C; Department of Pharmacy, University of Naples "Federico II", via D. Montesano 49, 80131, Naples, Italy.
  • Carino A; Department of Surgery and Biomedical Sciences, Nuova Facoltà di Medicina, Perugia, Italy.
  • De Marino S; Department of Pharmacy, University of Naples "Federico II", via D. Montesano 49, 80131, Naples, Italy.
  • Marchianò S; Department of Surgery and Biomedical Sciences, Nuova Facoltà di Medicina, Perugia, Italy.
  • Di Marino D; Università della Svizzera italiana (USI), Faculty of Biomedical Sciences, Institute of Computational Science - Center for Computational Medicine in Cardiology, Via G. Buffi 13, CH-6900, Lugano, Switzerland.
  • Finamore C; Department of Pharmacy, University of Naples "Federico II", via D. Montesano 49, 80131, Naples, Italy.
  • Monti MC; Department of Pharmacy, University of Salerno, Via Giovanni Paolo II, 132, 84084, Fisciano, Salerno, Italy.
  • Zampella A; Department of Pharmacy, University of Naples "Federico II", via D. Montesano 49, 80131, Naples, Italy.
  • Fiorucci S; Department of Surgery and Biomedical Sciences, Nuova Facoltà di Medicina, Perugia, Italy.
  • Limongelli V; Department of Pharmacy, University of Naples "Federico II", via D. Montesano 49, 80131, Naples, Italy. vittoriolimongelli@gmail.com.
Sci Rep ; 9(1): 2504, 2019 02 21.
Article em En | MEDLINE | ID: mdl-30792450
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Ureia / Bile / Ácidos e Sais Biliares / Receptores Acoplados a Proteínas G Limite: Humans Idioma: En Ano de publicação: 2019 Tipo de documento: Article
Texto completo
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Ureia / Bile / Ácidos e Sais Biliares / Receptores Acoplados a Proteínas G Limite: Humans Idioma: En Ano de publicação: 2019 Tipo de documento: Article