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Imidazole Ketone Erastin Induces Ferroptosis and Slows Tumor Growth in a Mouse Lymphoma Model.
Zhang, Yan; Tan, Hui; Daniels, Jacob D; Zandkarimi, Fereshteh; Liu, Hengrui; Brown, Lewis M; Uchida, Koji; O'Connor, Owen A; Stockwell, Brent R.
Afiliação
  • Zhang Y; Department of Chemistry, Columbia University, New York, NY 10027, USA.
  • Tan H; Department of Chemistry, Columbia University, New York, NY 10027, USA.
  • Daniels JD; Department of Pharmacology, Columbia University Medical Center, New York, NY 10032, USA.
  • Zandkarimi F; Department of Biological Sciences, Columbia University, New York, NY 10027, USA; Quantitative Proteomics and Metabolomics Center, Columbia University, New York, NY 10027, USA.
  • Liu H; Department of Chemistry, Columbia University, New York, NY 10027, USA.
  • Brown LM; Department of Biological Sciences, Columbia University, New York, NY 10027, USA; Quantitative Proteomics and Metabolomics Center, Columbia University, New York, NY 10027, USA.
  • Uchida K; Graduate School of Agricultural and Life Sciences, The University of Tokyo, Tokyo 113-8657, Japan.
  • O'Connor OA; Center for Lymphoid Malignancies, Columbia University Medical Center, College of Physicians and Surgeons, New York, NY 10019, USA.
  • Stockwell BR; Department of Chemistry, Columbia University, New York, NY 10027, USA; Department of Biological Sciences, Columbia University, New York, NY 10027, USA. Electronic address: bstockwell@columbia.edu.
Cell Chem Biol ; 26(5): 623-633.e9, 2019 05 16.
Article em En | MEDLINE | ID: mdl-30799221
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Piperazinas / Ferroptose / Imidazóis / Cetonas / Antineoplásicos Limite: Animals / Female / Humans / Male Idioma: En Ano de publicação: 2019 Tipo de documento: Article
Texto completo
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Piperazinas / Ferroptose / Imidazóis / Cetonas / Antineoplásicos Limite: Animals / Female / Humans / Male Idioma: En Ano de publicação: 2019 Tipo de documento: Article