The thioredoxin-1 and glutathione/glutaredoxin-1 systems redundantly fuel murine B-cell development and responses.

Muri, Jonathan; Thut, Helen; Heer, Sebastian; Krueger, Caroline C; Bornkamm, Georg W; Bachmann, Martin F; Kopf, Manfred

Muri, Jonathan; Thut, Helen; Heer, Sebastian; Krueger, Caroline C; Bornkamm, Georg W; Bachmann, Martin F; Kopf, Manfred.

Afiliação

Muri J; Institute of Molecular Health Sciences, ETH Zurich, Zürich, Switzerland.
Thut H; Institute of Molecular Health Sciences, ETH Zurich, Zürich, Switzerland.
Heer S; Institute of Molecular Health Sciences, ETH Zurich, Zürich, Switzerland.
Krueger CC; Department of BioMedical Research, University of Bern, Department of Immunology RIA, University Hospital Bern, Bern, Switzerland.
Bornkamm GW; Institute of Clinical Molecular Biology and Tumor Genetics, Helmholtz Zentrum München, München, Germany.
Bachmann MF; Department of BioMedical Research, University of Bern, Department of Immunology RIA, University Hospital Bern, Bern, Switzerland.
Kopf M; Institute of Molecular Health Sciences, ETH Zurich, Zürich, Switzerland.

Eur J Immunol ; 49(5): 709-723, 2019 05.

Article em En | MEDLINE | ID: mdl-30802940

Assuntos

Linfócitos B/imunologia; Linfócitos B/metabolismo; Diferenciação Celular/genética; Diferenciação Celular/imunologia; Glutarredoxinas/genética; Tiorredoxinas/genética; Animais; Linfócitos B/citologia; Biomarcadores; Proliferação de Células/genética; Centro Germinativo/imunologia; Centro Germinativo/metabolismo; Glutarredoxinas/metabolismo; Camundongos; Camundongos Transgênicos; Tiorredoxinas/metabolismo

Palavras-chave

Antibody responses; B cell development; Glutaredoxin-1; Thioredoxin-1

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Tiorredoxinas / Linfócitos B / Diferenciação Celular / Glutarredoxinas Limite: Animals Idioma: En Ano de publicação: 2019 Tipo de documento: Article

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