Assessment of pulsatile insulin secretion derived from peripheral plasma C-peptide concentrations by nonparametric stochastic deconvolution.

Laurenti, Marcello C; Vella, Adrian; Varghese, Ron T; Andrews, James C; Sharma, Anu; Kittah, Nana Esi; Rizza, Robert A; Matveyenko, Aleksey; De Nicolao, Giuseppe; Cobelli, Claudio; Dalla Man, Chiara

Laurenti, Marcello C; Vella, Adrian; Varghese, Ron T; Andrews, James C; Sharma, Anu; Kittah, Nana Esi; Rizza, Robert A; Matveyenko, Aleksey; De Nicolao, Giuseppe; Cobelli, Claudio; Dalla Man, Chiara.

Afiliação

Laurenti MC; Division of Endocrinology, Diabetes and Metabolism, Mayo Clinic , Rochester, Minnesota.
Vella A; Department of Information Engineering, University of Padua , Padua , Italy.
Varghese RT; Division of Endocrinology, Diabetes and Metabolism, Mayo Clinic , Rochester, Minnesota.
Andrews JC; Division of Endocrinology, Diabetes and Metabolism, Mayo Clinic , Rochester, Minnesota.
Sharma A; Vascular and Interventional Radiology, Mayo Clinic , Rochester, Minnesota.
Kittah NE; Division of Endocrinology, Diabetes and Metabolism, Mayo Clinic , Rochester, Minnesota.
Rizza RA; Division of Endocrinology, Diabetes and Metabolism, Mayo Clinic , Rochester, Minnesota.
Matveyenko A; Division of Endocrinology, Diabetes and Metabolism, Mayo Clinic , Rochester, Minnesota.
De Nicolao G; Division of Endocrinology, Diabetes and Metabolism, Mayo Clinic , Rochester, Minnesota.
Cobelli C; Physiology and Biomedical Engineering, Mayo Clinic , Rochester, Minnesota.
Dalla Man C; Department of Computer Engineering and Systems Science, University of Pavia , Pavia , Italy.

Am J Physiol Endocrinol Metab ; 316(5): E687-E694, 2019 05 01.

Article em En | MEDLINE | ID: mdl-30807214

Assuntos

Peptídeo C/sangue; Hiperglicemia/sangue; Secreção de Insulina/fisiologia; Insulina/sangue; Adulto; Peptídeo C/metabolismo; Simulação por Computador; Diabetes Mellitus Tipo 2/metabolismo; Feminino; Glucose/metabolismo; Voluntários Saudáveis; Veias Hepáticas; Humanos; Hiperglicemia/metabolismo; Insulina/metabolismo; Cinética; Masculino; Pessoa de Meia-Idade; Estatísticas não Paramétricas

Palavras-chave

C-peptide kinetics; diabetes; hepatic extraction; insulin pulses

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Peptídeo C / Secreção de Insulina / Hiperglicemia / Insulina Tipo de estudo: Prognostic_studies Limite: Adult / Female / Humans / Male / Middle aged Idioma: En Ano de publicação: 2019 Tipo de documento: Article

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