Curcumin suppresses wilms' tumor metastasis by inhibiting RECK methylation.

Jia, Wei; Deng, Fuming; Fu, Wen; Hu, Jinhua; Chen, Guifang; Gao, Xiaofeng; Tan, Xiangliang; Li, Guoyuan; Liu, Guochang; Zhu, Shibo

Jia, Wei; Deng, Fuming; Fu, Wen; Hu, Jinhua; Chen, Guifang; Gao, Xiaofeng; Tan, Xiangliang; Li, Guoyuan; Liu, Guochang; Zhu, Shibo.

Afiliação

Jia W; Department of Pediatric Urology, Guangzhou Women and Children's Medical Center, Guangzhou Medical University, Guangzhou 510623, Guangdong, China. Electronic address: jiawei198044@hotmail.com.
Deng F; Department of Pediatric Urology, Guangzhou Women and Children's Medical Center, Guangzhou Medical University, Guangzhou 510623, Guangdong, China.
Fu W; Department of Pediatric Urology, Guangzhou Women and Children's Medical Center, Guangzhou Medical University, Guangzhou 510623, Guangdong, China.
Hu J; Department of Pediatric Urology, Guangzhou Women and Children's Medical Center, Guangzhou Medical University, Guangzhou 510623, Guangdong, China.
Chen G; Department of Pediatric Urology, Guangzhou Women and Children's Medical Center, Guangzhou Medical University, Guangzhou 510623, Guangdong, China.
Gao X; Department of Pediatric Urology, Guangzhou Women and Children's Medical Center, Guangzhou Medical University, Guangzhou 510623, Guangdong, China.
Tan X; Department of Pediatric Urology, Guangzhou Women and Children's Medical Center, Guangzhou Medical University, Guangzhou 510623, Guangdong, China.
Li G; Department of Pediatric Urology, Guangzhou Women and Children's Medical Center, Guangzhou Medical University, Guangzhou 510623, Guangdong, China.
Liu G; Department of Pediatric Urology, Guangzhou Women and Children's Medical Center, Guangzhou Medical University, Guangzhou 510623, Guangdong, China.
Zhu S; Department of Pediatric Urology, Guangzhou Women and Children's Medical Center, Guangzhou Medical University, Guangzhou 510623, Guangdong, China. Electronic address: doctorzhushibo@163.com.

Biomed Pharmacother ; 111: 1204-1212, 2019 Mar.

Article em En | MEDLINE | ID: mdl-30841433

Assuntos

Curcumina/farmacologia; Metilação de DNA/efeitos dos fármacos; Proteínas Ligadas por GPI/genética; Neoplasias Renais/tratamento farmacológico; Metástase Neoplásica/tratamento farmacológico; Tumor de Wilms/tratamento farmacológico; Animais; Apoptose/efeitos dos fármacos; Apoptose/genética; Biomarcadores Tumorais/genética; Carcinogênese/efeitos dos fármacos; Carcinogênese/genética; Carcinogênese/patologia; Movimento Celular/efeitos dos fármacos; Movimento Celular/genética; Proliferação de Células/efeitos dos fármacos; Proliferação de Células/genética; Pré-Escolar; Regulação para Baixo/efeitos dos fármacos; Regulação para Baixo/genética; Feminino; Humanos; Neoplasias Renais/genética; Neoplasias Renais/patologia; Masculino; Metaloproteinase 2 da Matriz/genética; Metaloproteinase 9 da Matriz/genética; Camundongos; Camundongos Nus; Metástase Neoplásica/genética; Metástase Neoplásica/patologia; Tumor de Wilms/genética; Tumor de Wilms/patologia

Palavras-chave

Curcumin; Metastasis; Methylation; RECK; Wilms' tumor

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Tumor de Wilms / Metilação de DNA / Curcumina / Proteínas Ligadas por GPI / Neoplasias Renais / Metástase Neoplásica Tipo de estudo: Prognostic_studies Limite: Animals / Child, preschool / Female / Humans / Male Idioma: En Ano de publicação: 2019 Tipo de documento: Article

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