Bone marrow mesenchymal stem cell-derived exosomes alleviate high phosphorus-induced vascular smooth muscle cells calcification by modifying microRNA profiles.

Guo, Yan; Bao, Shumin; Guo, Wang; Diao, Zongli; Wang, Liyan; Han, Xue; Guo, Weikang; Liu, Wenhu

Guo, Yan; Bao, Shumin; Guo, Wang; Diao, Zongli; Wang, Liyan; Han, Xue; Guo, Weikang; Liu, Wenhu.

Afiliação

Guo Y; Department of Nephrology, Beijing Friendship Hospital, Faculty of Kidney Diseases, Capital Medical University, Beijing, 100050, China.
Bao S; Department of Nephrology, Beijing Friendship Hospital, Faculty of Kidney Diseases, Capital Medical University, Beijing, 100050, China.
Guo W; Department of Nephrology, Beijing Friendship Hospital, Faculty of Kidney Diseases, Capital Medical University, Beijing, 100050, China.
Diao Z; Department of Nephrology, Beijing Friendship Hospital, Faculty of Kidney Diseases, Capital Medical University, Beijing, 100050, China.
Wang L; Department of Nephrology, Beijing Friendship Hospital, Faculty of Kidney Diseases, Capital Medical University, Beijing, 100050, China.
Han X; Department of Nephrology, Beijing Friendship Hospital, Faculty of Kidney Diseases, Capital Medical University, Beijing, 100050, China.
Guo W; Department of Nephrology, Beijing Friendship Hospital, Faculty of Kidney Diseases, Capital Medical University, Beijing, 100050, China. gwk0777@qq.com.
Liu W; Department of Nephrology, Beijing Friendship Hospital, Faculty of Kidney Diseases, Capital Medical University, Beijing, 100050, China. liuwh0211@126.com.

Funct Integr Genomics ; 19(4): 633-643, 2019 Jul.

Article em En | MEDLINE | ID: mdl-30850904

Assuntos

Exossomos/metabolismo; Células-Tronco Mesenquimais/metabolismo; MicroRNAs/genética; Músculo Liso Vascular/metabolismo; Miócitos de Músculo Liso/metabolismo; Calcificação Vascular/metabolismo; Fosfatase Alcalina/metabolismo; Cálcio/metabolismo; Células Cultivadas; Exossomos/genética; Redes Reguladoras de Genes; Humanos; MicroRNAs/metabolismo; Fósforo/toxicidade; Transcriptoma; Regulação para Cima; Calcificação Vascular/etiologia; Calcificação Vascular/genética

Palavras-chave

Bone mesenchymal stem cells; Chronic kidney disease; Exosomes; MicroRNA; Vascular calcification

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Miócitos de Músculo Liso / MicroRNAs / Exossomos / Células-Tronco Mesenquimais / Calcificação Vascular / Músculo Liso Vascular Tipo de estudo: Etiology_studies / Prognostic_studies Limite: Humans Idioma: En Ano de publicação: 2019 Tipo de documento: Article

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