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Synthesis and pharmacological evaluation of novel arylpiperazine oxicams derivatives as potent analgesics without ulcerogenicity.
Szczesniak-Siega, Berenika M; Mogilski, Szczepan; Wiglusz, Rafal J; Janczak, Jan; Maniewska, Jadwiga; Malinka, Wieslaw; Filipek, Barbara.
Afiliação
  • Szczesniak-Siega BM; Department of Chemistry of Drugs, Faculty of Pharmacy, Wroclaw Medical University, Borowska 211, 50-556 Wroclaw, Poland. Electronic address: berenika.szczesniak-siega@umed.wroc.pl.
  • Mogilski S; Department of Pharmacodynamics, Faculty of Pharmacy, Medical College, Jagiellonian University, Medyczna 9, 30-688 Krakow, Poland.
  • Wiglusz RJ; Institute of Low Temperature and Structure Research, Polish Academy of Sciences, P.O. Box 1410, 50-950 Wroclaw, Poland; Centre for Advanced Materials and Smart Structures, Polish Academy of Sciences, Okólna 2, 50-950 Wroclaw, Poland.
  • Janczak J; Institute of Low Temperature and Structure Research, Polish Academy of Sciences, P.O. Box 1410, 50-950 Wroclaw, Poland.
  • Maniewska J; Department of Chemistry of Drugs, Faculty of Pharmacy, Wroclaw Medical University, Borowska 211, 50-556 Wroclaw, Poland.
  • Malinka W; Department of Chemistry of Drugs, Faculty of Pharmacy, Wroclaw Medical University, Borowska 211, 50-556 Wroclaw, Poland.
  • Filipek B; Department of Pharmacodynamics, Faculty of Pharmacy, Medical College, Jagiellonian University, Medyczna 9, 30-688 Krakow, Poland.
Bioorg Med Chem ; 27(8): 1619-1628, 2019 04 15.
Article em En | MEDLINE | ID: mdl-30852078
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Piperazinas / Anti-Inflamatórios não Esteroides / Analgésicos Limite: Animals Idioma: En Ano de publicação: 2019 Tipo de documento: Article
Texto completo
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XML
PubMed Links
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Piperazinas / Anti-Inflamatórios não Esteroides / Analgésicos Limite: Animals Idioma: En Ano de publicação: 2019 Tipo de documento: Article