Glucocorticoid Receptor Stimulation Resulting from Early Life Stress Affects Expression of DNA Methyltransferases in Rat Prefrontal Cortex.

Urb, Mari; Anier, Kaili; Matsalu, Terje; Aonurm-Helm, Anu; Tasa, Gunnar; Koppel, Indrek; Zharkovsky, Alexander; Timmusk, Tõnis; Kalda, Anti

Urb, Mari; Anier, Kaili; Matsalu, Terje; Aonurm-Helm, Anu; Tasa, Gunnar; Koppel, Indrek; Zharkovsky, Alexander; Timmusk, Tõnis; Kalda, Anti.

Afiliação

Urb M; Department of Pharmacology, Institute of Biomedicine and Translational Medicine, University of Tartu, 19 Ravila Street, 50411, Tartu, Estonia.
Anier K; Department of Pharmacology, Institute of Biomedicine and Translational Medicine, University of Tartu, 19 Ravila Street, 50411, Tartu, Estonia.
Matsalu T; Department of Pharmacology, Institute of Biomedicine and Translational Medicine, University of Tartu, 19 Ravila Street, 50411, Tartu, Estonia.
Aonurm-Helm A; Department of Pharmacology, Institute of Biomedicine and Translational Medicine, University of Tartu, 19 Ravila Street, 50411, Tartu, Estonia.
Tasa G; Department of Human Biology and Genetics, Institute of Biomedicine and Translational Medicine, University of Tartu, Tartu, Estonia.
Koppel I; Institute of Chemistry and Biotechnology, Tallinn University of Technology, Tallinn, Estonia.
Zharkovsky A; Department of Biomolecular Sciences, Weizmann Institute of Science, Rehovot, Israel.
Timmusk T; Department of Pharmacology, Institute of Biomedicine and Translational Medicine, University of Tartu, 19 Ravila Street, 50411, Tartu, Estonia.
Kalda A; Institute of Chemistry and Biotechnology, Tallinn University of Technology, Tallinn, Estonia.

J Mol Neurosci ; 68(1): 99-110, 2019 May.

Article em En | MEDLINE | ID: mdl-30852742

Assuntos

DNA-Citosina Metilases/genética; Córtex Pré-Frontal/metabolismo; Receptores de Glucocorticoides/metabolismo; Estresse Psicológico/metabolismo; Animais; Células Cultivadas; DNA-Citosina Metilases/metabolismo; Feminino; Masculino; Privação Materna; Regiões Promotoras Genéticas; Ligação Proteica; Ratos; Ratos Wistar; Estresse Psicológico/etiologia; Estresse Psicológico/genética

Palavras-chave

Corticosterone; DNA methyltransferase; Glucocorticoid receptor; Maternal separation; Prefrontal cortex; Rat

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Estresse Psicológico / DNA-Citosina Metilases / Receptores de Glucocorticoides / Córtex Pré-Frontal Tipo de estudo: Etiology_studies Limite: Animals Idioma: En Ano de publicação: 2019 Tipo de documento: Article

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