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A far-red fluorescent probe for sensing laccase in fungi and its application in developing an effective biocatalyst for the biosynthesis of antituberculous dicoumarin.
Tian, Zhenhao; Yan, Qingsong; Feng, Lei; Deng, Sa; Wang, Chao; Cui, Jingnan; Wang, Chunjie; Zhang, Zhanjun; James, Tony D; Ma, Xiaochi.
Afiliação
  • Tian Z; National-Local Joint Engineering Research Center for Drug-Research and Development of Neurodegenerative Disease, Academy of Integrative Medicine, College of Pharmacy, Dalian Medical University, Dalian, 116044, China. wach_edu@sina.com maxc1978@163.com and State Key Laboratory of Fine Chemicals, Dali
  • Yan Q; National-Local Joint Engineering Research Center for Drug-Research and Development of Neurodegenerative Disease, Academy of Integrative Medicine, College of Pharmacy, Dalian Medical University, Dalian, 116044, China. wach_edu@sina.com maxc1978@163.com.
  • Feng L; National-Local Joint Engineering Research Center for Drug-Research and Development of Neurodegenerative Disease, Academy of Integrative Medicine, College of Pharmacy, Dalian Medical University, Dalian, 116044, China. wach_edu@sina.com maxc1978@163.com and State Key Laboratory of Fine Chemicals, Dali
  • Deng S; National-Local Joint Engineering Research Center for Drug-Research and Development of Neurodegenerative Disease, Academy of Integrative Medicine, College of Pharmacy, Dalian Medical University, Dalian, 116044, China. wach_edu@sina.com maxc1978@163.com.
  • Wang C; National-Local Joint Engineering Research Center for Drug-Research and Development of Neurodegenerative Disease, Academy of Integrative Medicine, College of Pharmacy, Dalian Medical University, Dalian, 116044, China. wach_edu@sina.com maxc1978@163.com and State Key Laboratory of Fine Chemicals, Dali
  • Cui J; State Key Laboratory of Fine Chemicals, Dalian University of Technology, Dalian 116024, China.
  • Wang C; National-Local Joint Engineering Research Center for Drug-Research and Development of Neurodegenerative Disease, Academy of Integrative Medicine, College of Pharmacy, Dalian Medical University, Dalian, 116044, China. wach_edu@sina.com maxc1978@163.com.
  • Zhang Z; State Key Laboratory of Cognitive Neuroscience and Learning, Beijing Normal University, Beijing, China.
  • James TD; Department of Chemistry, University of Bath, Bath BA2 7AY, UK. t.d.james@bath.ac.uk.
  • Ma X; National-Local Joint Engineering Research Center for Drug-Research and Development of Neurodegenerative Disease, Academy of Integrative Medicine, College of Pharmacy, Dalian Medical University, Dalian, 116044, China. wach_edu@sina.com maxc1978@163.com.
Chem Commun (Camb) ; 55(27): 3951-3954, 2019 Apr 07.
Article em En | MEDLINE | ID: mdl-30874262
ABSTRACT
A far-red fluorescent probe has been developed for sensing fungal laccase. The probe was used to determine that Rhizopus oryzae had a high level endogenous laccase amongst 24 fungal strains. The Rhizopus oryzae was then used as a biocatalyst for the preparation of dicoumarin resulting in significant inhibition of Mycobacterium tuberculosis H37Ra.
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Rhizopus / Dicumarol / Lacase / Biocatálise / Corantes Fluorescentes / Mycobacterium tuberculosis / Antituberculosos Idioma: En Ano de publicação: 2019 Tipo de documento: Article
Texto completo
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Rhizopus / Dicumarol / Lacase / Biocatálise / Corantes Fluorescentes / Mycobacterium tuberculosis / Antituberculosos Idioma: En Ano de publicação: 2019 Tipo de documento: Article