Quantitative analysis of the effects of nicotinamide phosphoribosyltransferase induction on the rates of NAD+ synthesis and breakdown in mammalian cells using stable isotope-labeling combined with mass spectrometry.

Hara, Nobumasa; Osago, Harumi; Hiyoshi, Mineyoshi; Kobayashi-Miura, Mikiko; Tsuchiya, Mikako

Hara, Nobumasa; Osago, Harumi; Hiyoshi, Mineyoshi; Kobayashi-Miura, Mikiko; Tsuchiya, Mikako.

Afiliação

Hara N; Department of Biochemistry, Shimane University Faculty of Medicine, Izumo, Shimane, Japan.
Osago H; Department of Biochemistry, Shimane University Faculty of Medicine, Izumo, Shimane, Japan.
Hiyoshi M; Department of Biochemistry, Shimane University Faculty of Medicine, Izumo, Shimane, Japan.
Kobayashi-Miura M; Department of Biochemistry, Shimane University Faculty of Medicine, Izumo, Shimane, Japan.
Tsuchiya M; Department of Biochemistry, Shimane University Faculty of Medicine, Izumo, Shimane, Japan.

PLoS One ; 14(3): e0214000, 2019.

Article em En | MEDLINE | ID: mdl-30875389

Assuntos

NAD/metabolismo; Nicotinamida Fosforribosiltransferase/metabolismo; Animais; Tamanho Celular; Células Cultivadas; Humanos; Marcação por Isótopo; Cinética; Camundongos; Miócitos Cardíacos/metabolismo; NAD/biossíntese; Ratos; Espectrometria de Massas em Tandem

Texto completo

Imprimir

XML

PubMed Links

Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Nicotinamida Fosforribosiltransferase / NAD Limite: Animals / Humans Idioma: En Ano de publicação: 2019 Tipo de documento: Article

Texto completo

Imprimir

XML

PubMed Links

Buscar no Google