Your browser doesn't support javascript.
loading
Size-controlled synthesis of polymerized DNA nanoparticles for targeted anticancer drug delivery.
Nam, Keonwook; Kim, Taehyung; Kim, Young Min; Yang, Kyungjik; Choe, Deokyoung; Mensah, Lawrence B; Choi, Ki Young; Roh, Young Hoon.
Afiliação
  • Nam K; Department of Biotechnology, College of Life Science and Biotechnology, Yonsei University, 50 Yonsei-ro, Seodaemun-gu, Seoul 03722, Republic of Korea. yr36@yonsei.ac.kr.
Chem Commun (Camb) ; 55(34): 4905-4908, 2019 Apr 23.
Article em En | MEDLINE | ID: mdl-30901006
ABSTRACT
We synthesized size-tunable polymerized DNA nanoparticles (PDNs) for cancer-targeted drug delivery via sequential processes of rolling circle amplification, condensation, and layer-by-layer assembly. The PDNs selectively delivered anti-sense oligonucleotides to target cancer cells and exhibited size-dependent gene regulation efficacy.
Assuntos
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Neoplasias Ovarianas / DNA / Sistemas de Liberação de Medicamentos / Nanopartículas / Carcinoma Epitelial do Ovário / Antineoplásicos Limite: Animals / Female / Humans Idioma: En Ano de publicação: 2019 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Neoplasias Ovarianas / DNA / Sistemas de Liberação de Medicamentos / Nanopartículas / Carcinoma Epitelial do Ovário / Antineoplásicos Limite: Animals / Female / Humans Idioma: En Ano de publicação: 2019 Tipo de documento: Article