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Ellipticine-loaded apoferritin nanocarrier retains DNA adduct-based cytochrome P450-facilitated toxicity in neuroblastoma cells.
Indra, Radek; Cerná, Tereza; Heger, Zbynek; Hrabeta, Jan; Wilhelm, Marek; Dostálová, Simona; Lengálová, Alzbeta; Martínková, Markéta; Adam, Vojtech; Eckschlager, Tomás; Schmeiser, Heinz H; Arlt, Volker M; Stiborová, Marie.
Afiliação
  • Indra R; Department of Biochemistry, Faculty of Science, Charles University, Albertov 2030, 128 40, Prague 2, Czech Republic.
  • Cerná T; Department of Biochemistry, Faculty of Science, Charles University, Albertov 2030, 128 40, Prague 2, Czech Republic.
  • Heger Z; Department of Chemistry and Biochemistry, Mendel University in Brno, Zemedelska 1, 613 00, Brno, Czech Republic; Central European Institute of Technology, Brno University of Technology, Purkynova 123, 612 00, Brno, Czech Republic.
  • Hrabeta J; Department of Pediatric Hematology and Oncology, 2nd Medical Faculty, Charles University and University Hospital Motol, 150 06, Prague, Czech Republic.
  • Wilhelm M; Department of Biochemistry, Faculty of Science, Charles University, Albertov 2030, 128 40, Prague 2, Czech Republic.
  • Dostálová S; Department of Chemistry and Biochemistry, Mendel University in Brno, Zemedelska 1, 613 00, Brno, Czech Republic; Central European Institute of Technology, Brno University of Technology, Purkynova 123, 612 00, Brno, Czech Republic.
  • Lengálová A; Department of Biochemistry, Faculty of Science, Charles University, Albertov 2030, 128 40, Prague 2, Czech Republic.
  • Martínková M; Department of Biochemistry, Faculty of Science, Charles University, Albertov 2030, 128 40, Prague 2, Czech Republic.
  • Adam V; Department of Chemistry and Biochemistry, Mendel University in Brno, Zemedelska 1, 613 00, Brno, Czech Republic; Central European Institute of Technology, Brno University of Technology, Purkynova 123, 612 00, Brno, Czech Republic.
  • Eckschlager T; Department of Pediatric Hematology and Oncology, 2nd Medical Faculty, Charles University and University Hospital Motol, 150 06, Prague, Czech Republic.
  • Schmeiser HH; Division of Radiopharmaceutical Chemistry, German Cancer Research Center (DKFZ), Im Neuenheimer Feld 280, 69120, Heidelberg, Germany.
  • Arlt VM; Department of Analytical, Environmental and Forensic Sciences, MRC-PHE Centre for Environment and Health, King's College London, 150 Stamford Street, London, SE1 9NH, United Kingdom; NIHR Health Protection Research Unit in Health Impact of Environmental Hazards at King's College London in partnershi
  • Stiborová M; Department of Biochemistry, Faculty of Science, Charles University, Albertov 2030, 128 40, Prague 2, Czech Republic. Electronic address: stiborov@natur.cuni.cz.
Toxicology ; 419: 40-54, 2019 05 01.
Article em En | MEDLINE | ID: mdl-30914192
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Apoferritinas / Portadores de Fármacos / Adutos de DNA / Elipticinas / Citocromo P-450 CYP3A / Nanopartículas / Neuroblastoma / Antineoplásicos Limite: Humans Idioma: En Ano de publicação: 2019 Tipo de documento: Article
Texto completo
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XML
PubMed Links
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Apoferritinas / Portadores de Fármacos / Adutos de DNA / Elipticinas / Citocromo P-450 CYP3A / Nanopartículas / Neuroblastoma / Antineoplásicos Limite: Humans Idioma: En Ano de publicação: 2019 Tipo de documento: Article