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mTORC1 underlies age-related muscle fiber damage and loss by inducing oxidative stress and catabolism.
Tang, Huibin; Inoki, Ken; Brooks, Susan V; Okazawa, Hideki; Lee, Myung; Wang, Junying; Kim, Michael; Kennedy, Catherine L; Macpherson, Peter C D; Ji, Xuhuai; Van Roekel, Sabrina; Fraga, Danielle A; Wang, Kun; Zhu, Jinguo; Wang, Yoyo; Sharp, Zelton D; Miller, Richard A; Rando, Thomas A; Goldman, Daniel; Guan, Kun-Liang; Shrager, Joseph B.
Afiliação
  • Tang H; Division of Thoracic Surgery, Department of Cardiothoracic Surgery, Stanford University School of Medicine, Stanford, California.
  • Inoki K; VA Palo Alto Healthcare System, Palo Alto, California.
  • Brooks SV; Life Science Institute, University of Michigan, Ann Arbor, Michigan.
  • Okazawa H; Department of Molecular and Integrative Physiology, University of Michigan, Ann Arbor, Michigan.
  • Lee M; Department of Molecular and Integrative Physiology, University of Michigan, Ann Arbor, Michigan.
  • Wang J; Department of Pharmacology and Moores Cancer Center, University of California San Diego, La Jolla, California.
  • Kim M; Division of Thoracic Surgery, Department of Cardiothoracic Surgery, Stanford University School of Medicine, Stanford, California.
  • Kennedy CL; VA Palo Alto Healthcare System, Palo Alto, California.
  • Macpherson PCD; Life Science Institute, University of Michigan, Ann Arbor, Michigan.
  • Ji X; Division of Thoracic Surgery, Department of Cardiothoracic Surgery, Stanford University School of Medicine, Stanford, California.
  • Van Roekel S; VA Palo Alto Healthcare System, Palo Alto, California.
  • Fraga DA; Division of Thoracic Surgery, Department of Cardiothoracic Surgery, Stanford University School of Medicine, Stanford, California.
  • Wang K; VA Palo Alto Healthcare System, Palo Alto, California.
  • Zhu J; Molecular and Behavioral Neuroscience Institute and Department of Biological Chemistry, University of Michigan, Ann Arbor, Michigan.
  • Wang Y; Human Immune Monitoring Center, Stanford University School of Medicine, Stanford, California.
  • Sharp ZD; Department of Pathology and Geriatrics Center, University of Michigan, Ann Arbor, Michigan.
  • Miller RA; Division of Thoracic Surgery, Department of Cardiothoracic Surgery, Stanford University School of Medicine, Stanford, California.
  • Rando TA; VA Palo Alto Healthcare System, Palo Alto, California.
  • Goldman D; Division of Thoracic Surgery, Department of Cardiothoracic Surgery, Stanford University School of Medicine, Stanford, California.
  • Guan KL; VA Palo Alto Healthcare System, Palo Alto, California.
  • Shrager JB; Division of Thoracic Surgery, Department of Cardiothoracic Surgery, Stanford University School of Medicine, Stanford, California.
Aging Cell ; 18(3): e12943, 2019 06.
Article em En | MEDLINE | ID: mdl-30924297
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Envelhecimento / Estresse Oxidativo / Fibras Musculares Esqueléticas / Alvo Mecanístico do Complexo 1 de Rapamicina Limite: Animals / Humans Idioma: En Ano de publicação: 2019 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Envelhecimento / Estresse Oxidativo / Fibras Musculares Esqueléticas / Alvo Mecanístico do Complexo 1 de Rapamicina Limite: Animals / Humans Idioma: En Ano de publicação: 2019 Tipo de documento: Article