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Negative Co-stimulation Constrains T Cell Differentiation by Imposing Boundaries on Possible Cell States.
Wei, Spencer C; Sharma, Roshan; Anang, Nana-Ama A S; Levine, Jacob H; Zhao, Yang; Mancuso, James J; Setty, Manu; Sharma, Padmanee; Wang, Jing; Pe'er, Dana; Allison, James P.
Afiliação
  • Wei SC; Department of Immunology, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA.
  • Sharma R; Computational and Systems Biology Program, Sloan Kettering Institute, New York, NY 10065, USA; Department of Applied Physics and Applied Mathematics, Columbia University, New York, NY 10027, USA.
  • Anang NAS; Department of Immunology, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA.
  • Levine JH; Computational and Systems Biology Program, Sloan Kettering Institute, New York, NY 10065, USA.
  • Zhao Y; Department of Bioinformatics and Computational Biology, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA.
  • Mancuso JJ; Department of Immunology, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA.
  • Setty M; Computational and Systems Biology Program, Sloan Kettering Institute, New York, NY 10065, USA.
  • Sharma P; Department of Genitourinary Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA; Parker Institute for Cancer Immunotherapy, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA.
  • Wang J; Department of Bioinformatics and Computational Biology, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA.
  • Pe'er D; Computational and Systems Biology Program, Sloan Kettering Institute, New York, NY 10065, USA; Parker Institute for Cancer Immunotherapy, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA.
  • Allison JP; Department of Immunology, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA; Parker Institute for Cancer Immunotherapy, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA. Electronic address: jallison@mdanderson.org.
Immunity ; 50(4): 1084-1098.e10, 2019 04 16.
Article em En | MEDLINE | ID: mdl-30926234
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Ativação Linfocitária / Subpopulações de Linfócitos T / Linfopoese / Antígeno CTLA-4 / Receptor de Morte Celular Programada 1 Tipo de estudo: Prognostic_studies Limite: Animals Idioma: En Ano de publicação: 2019 Tipo de documento: Article
Texto completo
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Ativação Linfocitária / Subpopulações de Linfócitos T / Linfopoese / Antígeno CTLA-4 / Receptor de Morte Celular Programada 1 Tipo de estudo: Prognostic_studies Limite: Animals Idioma: En Ano de publicação: 2019 Tipo de documento: Article