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The Mitochondrial Transacylase, Tafazzin, Regulates for AML Stemness by Modulating Intracellular Levels of Phospholipids.
Seneviratne, Ayesh K; Xu, Mingjing; Henao, Juan J Aristizabal; Fajardo, Val A; Hao, Zhenyue; Voisin, Veronique; Xu, G Wei; Hurren, Rose; Kim, S; MacLean, Neil; Wang, Xiaoming; Gronda, Marcela; Jeyaraju, Danny; Jitkova, Yulia; Ketela, Troy; Mullokandov, Michael; Sharon, David; Thomas, Geethu; Chouinard-Watkins, Raphaël; Hawley, James R; Schafer, Caitlin; Yau, Helen Loo; Khuchua, Zaza; Aman, Ahmed; Al-Awar, Rima; Gross, Atan; Claypool, Steven M; Bazinet, Richard P; Lupien, Mathieu; Chan, Steven; De Carvalho, Daniel D; Minden, Mark D; Bader, Gary D; Stark, Ken D; LeBlanc, Paul; Schimmer, Aaron D.
Afiliação
  • Seneviratne AK; Princess Margaret Cancer Centre, University Health Network, Toronto, ON, Canada; Institute of Medical Sciences, Faculty of Medicine, University of Toronto, Toronto, ON, Canada.
  • Xu M; Princess Margaret Cancer Centre, University Health Network, Toronto, ON, Canada.
  • Henao JJA; Laboratory of Nutritional Lipidomics, Department of Kinesiology, University of Waterloo, Waterloo, ON, Canada.
  • Fajardo VA; Department of Health Sciences, Faculty of Applied Health Sciences, Brock University, St. Catharines, ON, Canada.
  • Hao Z; Princess Margaret Cancer Centre, University Health Network, Toronto, ON, Canada.
  • Voisin V; Department of Molecular Genetics, University of Toronto, Toronto, ON, Canada.
  • Xu GW; Princess Margaret Cancer Centre, University Health Network, Toronto, ON, Canada.
  • Hurren R; Princess Margaret Cancer Centre, University Health Network, Toronto, ON, Canada.
  • Kim S; Princess Margaret Cancer Centre, University Health Network, Toronto, ON, Canada.
  • MacLean N; Princess Margaret Cancer Centre, University Health Network, Toronto, ON, Canada.
  • Wang X; Princess Margaret Cancer Centre, University Health Network, Toronto, ON, Canada.
  • Gronda M; Princess Margaret Cancer Centre, University Health Network, Toronto, ON, Canada.
  • Jeyaraju D; Princess Margaret Cancer Centre, University Health Network, Toronto, ON, Canada.
  • Jitkova Y; Princess Margaret Cancer Centre, University Health Network, Toronto, ON, Canada.
  • Ketela T; Princess Margaret Cancer Centre, University Health Network, Toronto, ON, Canada.
  • Mullokandov M; Department of Biological Regulation, Weizmann Institute, Rehovot, Israel.
  • Sharon D; Princess Margaret Cancer Centre, University Health Network, Toronto, ON, Canada.
  • Thomas G; Princess Margaret Cancer Centre, University Health Network, Toronto, ON, Canada.
  • Chouinard-Watkins R; Department of Nutritional Sciences, Faculty of Medicine, University of Toronto, Toronto, ON, Canada.
  • Hawley JR; Princess Margaret Cancer Centre, University Health Network, Toronto, ON, Canada; Department of Medical Biophysics, University of Toronto, Toronto, ON, Canada.
  • Schafer C; Department of Pediatrics, College of Medicine, University of Cincinnati, Cincinnati, OH, USA.
  • Yau HL; Princess Margaret Cancer Centre, University Health Network, Toronto, ON, Canada; Department of Medical Biophysics, University of Toronto, Toronto, ON, Canada.
  • Khuchua Z; Department of Biochemistry, Sechenov Medical University, Moscow, Russian Federation; Institute of Medical Research Ilia State University, Tbilisi, Georgia.
  • Aman A; Drug Discovery Program, Ontario Institute for Cancer Research, Toronto, ON, Canada; Department of Pharmacology and Toxicology, University of Toronto, ON, Canada.
  • Al-Awar R; Drug Discovery Program, Ontario Institute for Cancer Research, Toronto, ON, Canada; Department of Pharmacology and Toxicology, University of Toronto, ON, Canada.
  • Gross A; Department of Biological Regulation, Weizmann Institute, Rehovot, Israel.
  • Claypool SM; Department of Physiology, School of Medicine, Johns Hopkins University, Baltimore, MD, USA.
  • Bazinet RP; Department of Nutritional Sciences, Faculty of Medicine, University of Toronto, Toronto, ON, Canada.
  • Lupien M; Princess Margaret Cancer Centre, University Health Network, Toronto, ON, Canada; Department of Medical Biophysics, University of Toronto, Toronto, ON, Canada.
  • Chan S; Princess Margaret Cancer Centre, University Health Network, Toronto, ON, Canada; Department of Medical Biophysics, University of Toronto, Toronto, ON, Canada.
  • De Carvalho DD; Princess Margaret Cancer Centre, University Health Network, Toronto, ON, Canada; Department of Medical Biophysics, University of Toronto, Toronto, ON, Canada.
  • Minden MD; Princess Margaret Cancer Centre, University Health Network, Toronto, ON, Canada; Department of Medical Biophysics, University of Toronto, Toronto, ON, Canada.
  • Bader GD; Department of Molecular Genetics, University of Toronto, Toronto, ON, Canada.
  • Stark KD; Laboratory of Nutritional Lipidomics, Department of Kinesiology, University of Waterloo, Waterloo, ON, Canada.
  • LeBlanc P; Department of Health Sciences, Faculty of Applied Health Sciences, Brock University, St. Catharines, ON, Canada.
  • Schimmer AD; Princess Margaret Cancer Centre, University Health Network, Toronto, ON, Canada; Institute of Medical Sciences, Faculty of Medicine, University of Toronto, Toronto, ON, Canada; Department of Medical Biophysics, University of Toronto, Toronto, ON, Canada. Electronic address: aaron.schimmer@uhn.ca.
Cell Stem Cell ; 24(4): 621-636.e16, 2019 04 04.
Article em En | MEDLINE | ID: mdl-30930145
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Fosfolipídeos / Fatores de Transcrição / Leucemia Mieloide Aguda / Mitocôndrias Tipo de estudo: Prognostic_studies Limite: Animals / Female / Humans / Male Idioma: En Ano de publicação: 2019 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Fosfolipídeos / Fatores de Transcrição / Leucemia Mieloide Aguda / Mitocôndrias Tipo de estudo: Prognostic_studies Limite: Animals / Female / Humans / Male Idioma: En Ano de publicação: 2019 Tipo de documento: Article