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Clinical and biological predictors of response to standardised paediatric colitis therapy (PROTECT): a multicentre inception cohort study.
Hyams, Jeffrey S; Davis Thomas, Sonia; Gotman, Nathan; Haberman, Yael; Karns, Rebekah; Schirmer, Melanie; Mo, Angela; Mack, David R; Boyle, Brendan; Griffiths, Anne M; LeLeiko, Neal S; Sauer, Cary G; Keljo, David J; Markowitz, James; Baker, Susan S; Rosh, Joel; Baldassano, Robert N; Patel, Ashish; Pfefferkorn, Marian; Otley, Anthony; Heyman, Melvin; Noe, Joshua; Oliva-Hemker, Maria; Rufo, Paul A; Strople, Jennifer; Ziring, David; Guthery, Stephen L; Sudel, Boris; Benkov, Keith; Wali, Prateek; Moulton, Dedrick; Evans, Jonathan; Kappelman, Michael D; Marquis, M Alison; Sylvester, Francisco A; Collins, Margaret H; Venkateswaran, Suresh; Dubinsky, Marla; Tangpricha, Vin; Spada, Krista L; Saul, Bradley; Wang, Jessie; Serrano, Jose; Hommel, Kevin; Marigorta, Urko M; Gibson, Greg; Xavier, Ramnik J; Kugathasan, Subra; Walters, Thomas; Denson, Lee A.
Afiliação
  • Hyams JS; Division of Digestive Diseases, Hepatology, and Nutrition, Connecticut Children's Medical Center, Hartford, CT, USA. Electronic address: jhyams@connecticutchildrens.org.
  • Davis Thomas S; Collaborative Studies Coordinating Center, University of North Carolina, Chapel Hill, NC, USA; Department of Biostatistics, University of North Carolina, Chapel Hill, NC, USA; RTI International, Research Triangle Park, NC, USA.
  • Gotman N; Collaborative Studies Coordinating Center, University of North Carolina, Chapel Hill, NC, USA.
  • Haberman Y; Division of Gastroenterology, Hepatology, and Nutrition, Cincinnati Children's Hospital Medical Center and the University of Cincinnati College of Medicine, Cincinnati, OH, USA; Sheba Medical Center, affiliated with the Tel Aviv University, Tel Hashomer, Israel.
  • Karns R; Division of Gastroenterology, Hepatology, and Nutrition, Cincinnati Children's Hospital Medical Center and the University of Cincinnati College of Medicine, Cincinnati, OH, USA.
  • Schirmer M; The Broad Institute of MIT and Harvard, Cambridge, MA, USA; Department of Biostatistics, Harvard T H Chan School of Public Health, Boston, MA, USA.
  • Mo A; Georgia Institute of Technology, Atlanta, GA, USA.
  • Mack DR; School of Biological Sciences, Children's Hospital of Eastern Ontario, University of Ottawa, Ottawa, ON, Canada.
  • Boyle B; Division of Pediatric Gastroenterology, Hepatology, and Nutrition, Nationwide Children's Hospital, Columbus, OH, USA.
  • Griffiths AM; Divisioin of Pediatric Gastroenterology, Hospital For Sick Children, Toronto, ON, Canada.
  • LeLeiko NS; IBD Centre, Department of Paediatrics, Hasbro Children's Hospital, Providence, RI, USA.
  • Sauer CG; Divisioin of Pediatric Gastroenterology, Nutritiion, and Liver Disease, Emory University, Atlanta, GA, USA.
  • Keljo DJ; Division of Gastroenterology, Children's Hospital of Pittsburgh, Pittsburgh, PA, USA.
  • Markowitz J; Division of Gastroenterology, Hepatology, and Nutrition, Cohen Children's Medical Center Of New York, New Hyde Park, NY, USA.
  • Baker SS; Division of Pediatric Gastroenterology, Hepatology, and Nutrition, Women & Children's Hospital of Buffalo WCHOB, Buffalo, NY, USA.
  • Rosh J; Division of Gastroenterology, Hepatology, and Nutrition, Goryeb Children's Hospital, Atlantic Health, Morristown, NJ, USA.
  • Baldassano RN; Division of Gastroenterology, Hepatology, and Nutrition, The Children's Hospital of Philadelphia, Philadelphia, PA, USA.
  • Patel A; Division of Gastroenterology, Hepatology, and Nutrition, UT Southwestern, Dallas, TX, USA.
  • Pfefferkorn M; Division of Gastroenterology, Hepatology, and Nutrition, Riley Children's Hospital Indiana, Indianapolis, IN, USA.
  • Otley A; Division of Gastroenterology, Hepatology, and Nutrition, IWK Health Centre, Halifax, NS, Canada.
  • Heyman M; Division of Gastroenterology, Hepatology, and Nutrition, University of California at San Francisco, San Francisco, CA, USA.
  • Noe J; Division of Gastroenterology, Hepatology, and Nutrition, Medical College of Wisconsin, Milwaukee, WI, USA.
  • Oliva-Hemker M; Division of Gastroenterology, Hepatology, and Nutrition, Johns Hopkins Children's Center, Baltimore, MD, USA.
  • Rufo PA; Division of Gastroenterology, Hepatology, and Nutrition, Children's Hospital Boston, Harvard Medical School Boston, MA, USA.
  • Strople J; Division of Gastroenterology, Ann & Robert H Lurie Children's Hospital of Chicago, Chicago, IL, USA.
  • Ziring D; Division of Gastroenterology, Hepatology, and Nutrition, UCLA Medical Center, Los Angeles, CA, USA.
  • Guthery SL; Division of Gastroenterology, Hepatology, and Nutrition, Primary Children's Hospital and the University of Utah, Salt Lake City, UT, USA.
  • Sudel B; Division of Gastroenterology, Hepatology, and Nutrition, University of Minnesota Medical Center, Minneapolis, MN, USA.
  • Benkov K; Division of Gastroenterology, Hepatology, and Nutrition, Mt Sinai Hospital, New York City, NY, USA.
  • Wali P; Division of Gastroenterology, Hepatology, and Nutrition, State University of New York Upstate Medical University, Syracuse, NY, USA.
  • Moulton D; Division of Gastroenterology, Hepatology, and Nutrition, Monroe Carell Jr Children's Hospital of Vanderbilt, Nashville, TN, USA.
  • Evans J; Division of Gastroenterology, Hepatology, and Nutrition, Nemours Children's Clinic, Jacksonville, FL, USA.
  • Kappelman MD; Department of Biostatistics, University of North Carolina, Chapel Hill, NC, USA.
  • Marquis MA; Collaborative Studies Coordinating Center, University of North Carolina, Chapel Hill, NC, USA.
  • Sylvester FA; Department of Biostatistics, University of North Carolina, Chapel Hill, NC, USA.
  • Collins MH; Division of Gastroenterology, Hepatology, and Nutrition, Cincinnati Children's Hospital Medical Center and the University of Cincinnati College of Medicine, Cincinnati, OH, USA.
  • Venkateswaran S; Divisioin of Pediatric Gastroenterology, Nutritiion, and Liver Disease, Emory University, Atlanta, GA, USA.
  • Dubinsky M; Division of Gastroenterology, Hepatology, and Nutrition, Mt Sinai Hospital, New York City, NY, USA.
  • Tangpricha V; Divisioin of Pediatric Gastroenterology, Nutritiion, and Liver Disease, Emory University, Atlanta, GA, USA.
  • Spada KL; Division of Digestive Diseases, Hepatology, and Nutrition, Connecticut Children's Medical Center, Hartford, CT, USA.
  • Saul B; Collaborative Studies Coordinating Center, University of North Carolina, Chapel Hill, NC, USA.
  • Wang J; Collaborative Studies Coordinating Center, University of North Carolina, Chapel Hill, NC, USA.
  • Serrano J; National Institutes of Diabetes, Digestive and Kidney Diseases, Bethesda, MD, USA.
  • Hommel K; Division of Gastroenterology, Hepatology, and Nutrition, Cincinnati Children's Hospital Medical Center and the University of Cincinnati College of Medicine, Cincinnati, OH, USA.
  • Marigorta UM; Georgia Institute of Technology, Atlanta, GA, USA.
  • Gibson G; Georgia Institute of Technology, Atlanta, GA, USA.
  • Xavier RJ; The Broad Institute of MIT and Harvard, Cambridge, MA, USA; Center for Computational and Integrative Biology, Gastrointestinal Unit, and Center for the Study of Inflammatory Bowel Disease, Massachusetts General Hospital, Boston, MA, USA; Center for Microbiome Informatics and Therapeutics, Massachuse
  • Kugathasan S; Divisioin of Pediatric Gastroenterology, Nutritiion, and Liver Disease, Emory University, Atlanta, GA, USA.
  • Walters T; Divisioin of Pediatric Gastroenterology, Hospital For Sick Children, Toronto, ON, Canada.
  • Denson LA; Division of Gastroenterology, Hepatology, and Nutrition, Cincinnati Children's Hospital Medical Center and the University of Cincinnati College of Medicine, Cincinnati, OH, USA.
Lancet ; 393(10182): 1708-1720, 2019 04 27.
Article em En | MEDLINE | ID: mdl-30935734
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Texto completo: 1 Eixos temáticos: Pesquisa_clinica Base de dados: MEDLINE Assunto principal: Colite Ulcerativa / Anti-Inflamatórios não Esteroides / Corticosteroides / Mesalamina Tipo de estudo: Clinical_trials / Etiology_studies / Guideline / Incidence_studies / Observational_studies / Prognostic_studies / Risk_factors_studies Limite: Adolescent / Child / Child, preschool / Female / Humans / Male Idioma: En Ano de publicação: 2019 Tipo de documento: Article
Texto completo
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Texto completo: 1 Eixos temáticos: Pesquisa_clinica Base de dados: MEDLINE Assunto principal: Colite Ulcerativa / Anti-Inflamatórios não Esteroides / Corticosteroides / Mesalamina Tipo de estudo: Clinical_trials / Etiology_studies / Guideline / Incidence_studies / Observational_studies / Prognostic_studies / Risk_factors_studies Limite: Adolescent / Child / Child, preschool / Female / Humans / Male Idioma: En Ano de publicação: 2019 Tipo de documento: Article