Dysregulation of microRNA-181b and TIMP3 is functionally involved in the pathogenesis of diabetic nephropathy.

Zhu, Fu-Xiang; Wu, Heng-Lan; Chen, Jian-Xiang; Han, Bin; Guo, Yin-Feng

Zhu, Fu-Xiang; Wu, Heng-Lan; Chen, Jian-Xiang; Han, Bin; Guo, Yin-Feng.

Afiliação

Zhu FX; Department of Nephrology, First Affiliated Hospital of Jiaxing University, Jiaxing, Zhejiang, China.
Wu HL; Department of Nephrology, First Affiliated Hospital of Jiaxing University, Jiaxing, Zhejiang, China.
Chen JX; Department of Nephrology, First Affiliated Hospital of Jiaxing University, Jiaxing, Zhejiang, China.
Han B; Department of Nephrology, First Affiliated Hospital of Jiaxing University, Jiaxing, Zhejiang, China.
Guo YF; Department of Nephrology, First Affiliated Hospital of Jiaxing University, Jiaxing, Zhejiang, China.

J Cell Physiol ; 234(10): 18963-18969, 2019 08.

Article em En | MEDLINE | ID: mdl-30937907

Assuntos

Diabetes Mellitus/patologia; Nefropatias Diabéticas/patologia; Células Mesangiais/metabolismo; MicroRNAs/genética; Inibidor Tecidual de Metaloproteinase-3/metabolismo; Apoptose/genética; Movimento Celular/fisiologia; Proliferação de Células/fisiologia; Sobrevivência Celular/fisiologia; Células Cultivadas; Feminino; Humanos; Masculino; Interferência de RNA; RNA Interferente Pequeno/genética; Inibidor Tecidual de Metaloproteinase-3/genética

Palavras-chave

TIMP3; apoptosis; diabetic nephropathy; mesangial cells; microRNA-181b

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Inibidor Tecidual de Metaloproteinase-3 / MicroRNAs / Diabetes Mellitus / Nefropatias Diabéticas / Células Mesangiais Tipo de estudo: Etiology_studies Limite: Female / Humans / Male Idioma: En Ano de publicação: 2019 Tipo de documento: Article

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