Edwardsiella tarda-induced miR-7a functions as a suppressor in PI3K/AKT/GSK3ß signaling pathway by targeting insulin receptor substrate-2 (IRS2a and IRS2b) in Paralichthys olivaceus.

Liu, Yuezhong; Liu, Yuxiang; Han, Miao; Du, Xinxin; Liu, Xiumei; Zhang, Quanqi; Liu, Jinxiang

Liu, Yuezhong; Liu, Yuxiang; Han, Miao; Du, Xinxin; Liu, Xiumei; Zhang, Quanqi; Liu, Jinxiang.

Afiliação

Liu Y; Key Laboratory of Marine Genetics and Breeding, Ministry of Education, Ocean University of China, Qingdao, 266003, China.
Liu Y; Key Laboratory of Marine Genetics and Breeding, Ministry of Education, Ocean University of China, Qingdao, 266003, China.
Han M; Key Laboratory of Marine Genetics and Breeding, Ministry of Education, Ocean University of China, Qingdao, 266003, China.
Du X; Key Laboratory of Marine Genetics and Breeding, Ministry of Education, Ocean University of China, Qingdao, 266003, China; Department of Life Science and Engineering, Jining University, Jining, China.
Liu X; Key Laboratory of Marine Genetics and Breeding, Ministry of Education, Ocean University of China, Qingdao, 266003, China; College of Life Sciences, Yantai University, Yantai, 264005, China.
Zhang Q; Key Laboratory of Marine Genetics and Breeding, Ministry of Education, Ocean University of China, Qingdao, 266003, China; Laboratory for Marine Fisheries Science and Food Production Processes, Qingdao National Laboratory for Marine Science and Technology, Qingdao, 266237, China.
Liu J; Key Laboratory of Marine Genetics and Breeding, Ministry of Education, Ocean University of China, Qingdao, 266003, China; Laboratory for Marine Fisheries Science and Food Production Processes, Qingdao National Laboratory for Marine Science and Technology, Qingdao, 266237, China. Electronic address:

Fish Shellfish Immunol ; 89: 477-485, 2019 Jun.

Article em En | MEDLINE | ID: mdl-30940579

Assuntos

Edwardsiella tarda/fisiologia; Proteínas de Peixes/genética; Linguados/imunologia; Proteínas Substratos do Receptor de Insulina/genética; MicroRNAs/metabolismo; Transdução de Sinais/genética; Animais; Proteínas de Peixes/metabolismo; Linguados/genética; Linguados/metabolismo; Proteínas Substratos do Receptor de Insulina/metabolismo

Palavras-chave

Edwardsiella tarda; High-throughput sequencing; IRS2; PI3K/AKT/GSK3ß pathway; Paralichthys olivaceus; miR-7a

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Linguados / Transdução de Sinais / Edwardsiella tarda / Proteínas de Peixes / MicroRNAs / Proteínas Substratos do Receptor de Insulina Limite: Animals Idioma: En Ano de publicação: 2019 Tipo de documento: Article

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