Variance Components Models for Analysis of Big Family Data of Health Outcomes in the Lifelines Cohort Study.

Demetrashvili, Nino; Smidt, Nynke; Snieder, Harold; van den Heuvel, Edwin R; Wit, Ernst C

Demetrashvili, Nino; Smidt, Nynke; Snieder, Harold; van den Heuvel, Edwin R; Wit, Ernst C.

Afiliação

Demetrashvili N; Department of Epidemiology,University of Groningen, University Medical Center Groningen,Groningen,The Netherlands.
Smidt N; Department of Epidemiology,University of Groningen, University Medical Center Groningen,Groningen,The Netherlands.
Snieder H; Department of Epidemiology,University of Groningen, University Medical Center Groningen,Groningen,The Netherlands.
van den Heuvel ER; Department of Epidemiology,University of Groningen, University Medical Center Groningen,Groningen,The Netherlands.
Wit EC; Bernoulli Institute,University of Groningen,Groningen,The Netherlands.

Twin Res Hum Genet ; 22(1): 4-13, 2019 02.

Article em En | MEDLINE | ID: mdl-30944055

Assuntos

Envelhecimento/genética; Big Data; Bases de Dados Genéticas; Família; Interação Gene-Ambiente; Modelos Genéticos; Feminino; Humanos; Masculino

Palavras-chave

Determinants and health outcome; founders and non-founders; fractional relatedness of family members; genetic and environmental factors; heritability and its confidence interval; kinship model; mental and physical health scores; mixed effects models

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Envelhecimento / Família / Bases de Dados Genéticas / Interação Gene-Ambiente / Big Data / Modelos Genéticos Tipo de estudo: Etiology_studies / Observational_studies / Prognostic_studies Limite: Female / Humans / Male Idioma: En Ano de publicação: 2019 Tipo de documento: Article

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