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Cotrimoxazole reduces systemic inflammation in HIV infection by altering the gut microbiome and immune activation.
Bourke, Claire D; Gough, Ethan K; Pimundu, Godfrey; Shonhai, Annie; Berejena, Chipo; Terry, Louise; Baumard, Lucas; Choudhry, Naheed; Karmali, Yusuf; Bwakura-Dangarembizi, Mutsa; Musiime, Victor; Lutaakome, Joseph; Kekitiinwa, Adeodata; Mutasa, Kuda; Szubert, Alexander J; Spyer, Moira J; Deayton, Jane R; Glass, Magdalena; Geum, Hyun Min; Pardieu, Claire; Gibb, Diana M; Klein, Nigel; Edens, Thaddeus J; Walker, A Sarah; Manges, Amee R; Prendergast, Andrew J.
Afiliação
  • Bourke CD; Blizard Institute, Queen Mary University of London, London E1 2AT, UK. c.bourke@qmul.ac.uk.
  • Gough EK; School of Population and Public Health, University of British Columbia, Vancouver, BC V6T 1Z3, Canada.
  • Pimundu G; Joint Clinical Research Centre, Kampala, Uganda.
  • Shonhai A; College of Health Sciences, University of Zimbabwe, Harare, Zimbabwe.
  • Berejena C; College of Health Sciences, University of Zimbabwe, Harare, Zimbabwe.
  • Terry L; Royal London Hospital, Barts Health NHS Trust, London E1 1BB, UK.
  • Baumard L; Blizard Institute, Queen Mary University of London, London E1 2AT, UK.
  • Choudhry N; Blizard Institute, Queen Mary University of London, London E1 2AT, UK.
  • Karmali Y; Blizard Institute, Queen Mary University of London, London E1 2AT, UK.
  • Bwakura-Dangarembizi M; College of Health Sciences, University of Zimbabwe, Harare, Zimbabwe.
  • Musiime V; Joint Clinical Research Centre, Kampala, Uganda.
  • Lutaakome J; College of Health Sciences, Department of Paediatrics and Child Health, Makerere University, Kampala, Uganda.
  • Kekitiinwa A; Uganda Virus Research Institute/MRC Uganda Research Unit on AIDS, Entebbe, Uganda.
  • Mutasa K; Baylor College of Medicine Children's Foundation-Uganda, Mulago Hospital, Kampala, Uganda.
  • Szubert AJ; Zvitambo Institute for Maternal and Child Health Research, Harare, Zimbabwe.
  • Spyer MJ; MRC Clinical Trials Unit at University College London, London WC1V 6LJ, UK.
  • Deayton JR; MRC Clinical Trials Unit at University College London, London WC1V 6LJ, UK.
  • Glass M; Blizard Institute, Queen Mary University of London, London E1 2AT, UK.
  • Geum HM; Royal London Hospital, Barts Health NHS Trust, London E1 1BB, UK.
  • Pardieu C; School of Population and Public Health, University of British Columbia, Vancouver, BC V6T 1Z3, Canada.
  • Gibb DM; School of Population and Public Health, University of British Columbia, Vancouver, BC V6T 1Z3, Canada.
  • Klein N; Blizard Institute, Queen Mary University of London, London E1 2AT, UK.
  • Edens TJ; MRC Clinical Trials Unit at University College London, London WC1V 6LJ, UK.
  • Walker AS; UCL Great Ormond Street Institute of Child Health, London WC1N 1EH, UK.
  • Manges AR; Devil's Staircase Consulting, West Vancouver, British Columbia V7T 1V7, Canada.
  • Prendergast AJ; MRC Clinical Trials Unit at University College London, London WC1V 6LJ, UK.
Sci Transl Med ; 11(486)2019 04 03.
Article em En | MEDLINE | ID: mdl-30944164
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Infecções por HIV / Combinação Trimetoprima e Sulfametoxazol / Microbioma Gastrointestinal / Inflamação Tipo de estudo: Clinical_trials Limite: Child / Child, preschool / Humans Idioma: En Ano de publicação: 2019 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Infecções por HIV / Combinação Trimetoprima e Sulfametoxazol / Microbioma Gastrointestinal / Inflamação Tipo de estudo: Clinical_trials Limite: Child / Child, preschool / Humans Idioma: En Ano de publicação: 2019 Tipo de documento: Article