Managing Neuronal Ensembles: Somatostatin Interneuron Subpopulations Shape and Protect Cortical Neuronal Ensembles for Learning.

ABSTRACT

Learning is accompanied by temporal compression and sharpening of neuronal firing sequences. In this issue of Neuron, Adler et al. (2019), using a motor skill paradigm and its variant, uncover a dual role for somatostatin interneuron regulation to support ensemble compaction and protection in learning.