The expression of <i>TAP1</i> candidate gene, but not its polymorphism and methylation, is associated with colonic polyp formation in a porcine model of human familial adenomatous polyposis.

Perkowska, Anna; Flisikowska, Tatiana; Perleberg, Carolin; Flisikowski, Krzysztof; Stachowiak, Monika; Nowacka-Woszuk, Joanna; Saur, Dieter; Kind, Alexander; Schnieke, Angelika; Switonski, Marek

The expression of TAP1 candidate gene, but not its polymorphism and methylation, is associated with colonic polyp formation in a porcine model of human familial adenomatous polyposis.

Perkowska, Anna; Flisikowska, Tatiana; Perleberg, Carolin; Flisikowski, Krzysztof; Stachowiak, Monika; Nowacka-Woszuk, Joanna; Saur, Dieter; Kind, Alexander; Schnieke, Angelika; Switonski, Marek.

Afiliação

Perkowska A; Department of Genetics and Animal Breeding, Poznan University of Life Sciences, Poznan, Poland.
Flisikowska T; Chair of Livestock Biotechnology, Technical University of Munich, Freising, Germany.
Perleberg C; Chair of Livestock Biotechnology, Technical University of Munich, Freising, Germany.
Flisikowski K; Chair of Livestock Biotechnology, Technical University of Munich, Freising, Germany.
Stachowiak M; Department of Genetics and Animal Breeding, Poznan University of Life Sciences, Poznan, Poland.
Nowacka-Woszuk J; Department of Genetics and Animal Breeding, Poznan University of Life Sciences, Poznan, Poland.
Saur D; Klinikum Rechts der Isar II, Technical University of Munich, Munich, Germany.
Kind A; Chair of Livestock Biotechnology, Technical University of Munich, Freising, Germany.
Schnieke A; Chair of Livestock Biotechnology, Technical University of Munich, Freising, Germany.
Switonski M; Department of Genetics and Animal Breeding, Poznan University of Life Sciences, Poznan, Poland.

Anim Biotechnol ; 31(4): 306-313, 2020 Aug.

Article em En | MEDLINE | ID: mdl-30950765

Assuntos

Membro 2 da Subfamília B de Transportadores de Cassetes de Ligação de ATP; Polipose Adenomatosa do Colo; Pólipos do Colo; Metilação de DNA/genética; Polimorfismo de Nucleotídeo Único/genética; Membro 2 da Subfamília B de Transportadores de Cassetes de Ligação de ATP/genética; Membro 2 da Subfamília B de Transportadores de Cassetes de Ligação de ATP/metabolismo; Polipose Adenomatosa do Colo/epidemiologia; Polipose Adenomatosa do Colo/genética; Animais; Pólipos do Colo/epidemiologia; Pólipos do Colo/genética; Modelos Animais de Doenças; Humanos; Mutação; Suínos

Palavras-chave

CRC; FAP; SEAP; TAP1; methylation; pig

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Pólipos do Colo / Polipose Adenomatosa do Colo / Metilação de DNA / Polimorfismo de Nucleotídeo Único / Membro 2 da Subfamília B de Transportadores de Cassetes de Ligação de ATP Tipo de estudo: Prognostic_studies / Risk_factors_studies Limite: Animals / Humans Idioma: En Ano de publicação: 2020 Tipo de documento: Article

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