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Peptides conjugated to 2-alkoxy-8-oxo-adenine as potential synthetic vaccines triggering TLR7.
Gential, Geoffroy P P; Hogervorst, Tim P; Tondini, Elena; van de Graaff, Michel J; Overkleeft, Herman S; Codée, Jeroen D C; van der Marel, Gijsbert A; Ossendorp, Ferry; Filippov, Dmitri V.
Afiliação
  • Gential GPP; Leiden Institute of Chemistry and The Institute for Chemical Immunology, Leiden University, Einsteinweg 55, 2333 CC Leiden, The Netherlands.
  • Hogervorst TP; Leiden Institute of Chemistry and The Institute for Chemical Immunology, Leiden University, Einsteinweg 55, 2333 CC Leiden, The Netherlands.
  • Tondini E; Department of Immunohematology and Blood Transfusion, Leiden University Medical Center, P.O. Box 9600, 2300 RC Leiden, The Netherlands.
  • van de Graaff MJ; Leiden Institute of Chemistry and The Institute for Chemical Immunology, Leiden University, Einsteinweg 55, 2333 CC Leiden, The Netherlands.
  • Overkleeft HS; Leiden Institute of Chemistry and The Institute for Chemical Immunology, Leiden University, Einsteinweg 55, 2333 CC Leiden, The Netherlands.
  • Codée JDC; Leiden Institute of Chemistry and The Institute for Chemical Immunology, Leiden University, Einsteinweg 55, 2333 CC Leiden, The Netherlands.
  • van der Marel GA; Leiden Institute of Chemistry and The Institute for Chemical Immunology, Leiden University, Einsteinweg 55, 2333 CC Leiden, The Netherlands.
  • Ossendorp F; Department of Immunohematology and Blood Transfusion, Leiden University Medical Center, P.O. Box 9600, 2300 RC Leiden, The Netherlands.
  • Filippov DV; Leiden Institute of Chemistry and The Institute for Chemical Immunology, Leiden University, Einsteinweg 55, 2333 CC Leiden, The Netherlands. Electronic address: filippov@chem.leidenuniv.nl.
Bioorg Med Chem Lett ; 29(11): 1340-1344, 2019 06 01.
Article em En | MEDLINE | ID: mdl-30952595
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Peptídeos / Vacinas Sintéticas / Adenina / Receptor 7 Toll-Like Limite: Humans Idioma: En Ano de publicação: 2019 Tipo de documento: Article
Texto completo
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XML
PubMed Links
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Peptídeos / Vacinas Sintéticas / Adenina / Receptor 7 Toll-Like Limite: Humans Idioma: En Ano de publicação: 2019 Tipo de documento: Article