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Metabolic resistance of the D-peptide RD2 developed for direct elimination of amyloid-ß oligomers.
Elfgen, Anne; Hupert, Michelle; Bochinsky, Kevin; Tusche, Markus; González de San Román Martin, Estibaliz; Gering, Ian; Sacchi, Silvia; Pollegioni, Loredano; Huesgen, Pitter F; Hartmann, Rudolf; Santiago-Schübel, Beatrix; Kutzsche, Janine; Willbold, Dieter.
Afiliação
  • Elfgen A; Institute of Complex Systems, Structural Biochemistry (ICS-6), Research Center Jülich, 52428, Jülich, Germany.
  • Hupert M; Central Institute for Engineering, Electronics and Analytics (ZEA-3), Research Center Jülich, 52428, Jülich, Germany.
  • Bochinsky K; Institute of Complex Systems, Structural Biochemistry (ICS-6), Research Center Jülich, 52428, Jülich, Germany.
  • Tusche M; Institute of Complex Systems, Structural Biochemistry (ICS-6), Research Center Jülich, 52428, Jülich, Germany.
  • González de San Román Martin E; Central Institute for Engineering, Electronics and Analytics (ZEA-3), Research Center Jülich, 52428, Jülich, Germany.
  • Gering I; Institute of Complex Systems, Structural Biochemistry (ICS-6), Research Center Jülich, 52428, Jülich, Germany.
  • Sacchi S; Dipartimento di Biotecnologie e Scienze della Vita, Università dell'Insubria, 21100, Varese, Italy.
  • Pollegioni L; The Protein Factory Research Center, Università dell'Insubria and Politecnico di Milano, 20100, Milano, Italy.
  • Huesgen PF; Dipartimento di Biotecnologie e Scienze della Vita, Università dell'Insubria, 21100, Varese, Italy.
  • Hartmann R; The Protein Factory Research Center, Università dell'Insubria and Politecnico di Milano, 20100, Milano, Italy.
  • Santiago-Schübel B; Central Institute for Engineering, Electronics and Analytics (ZEA-3), Research Center Jülich, 52428, Jülich, Germany.
  • Kutzsche J; Institute of Complex Systems, Structural Biochemistry (ICS-6), Research Center Jülich, 52428, Jülich, Germany.
  • Willbold D; Central Institute for Engineering, Electronics and Analytics (ZEA-3), Research Center Jülich, 52428, Jülich, Germany.
Sci Rep ; 9(1): 5715, 2019 04 05.
Article em En | MEDLINE | ID: mdl-30952881
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Oligopeptídeos / Peptídeos beta-Amiloides / Trato Gastrointestinal / Fígado Limite: Animals / Humans Idioma: En Ano de publicação: 2019 Tipo de documento: Article
Texto completo
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XML
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Oligopeptídeos / Peptídeos beta-Amiloides / Trato Gastrointestinal / Fígado Limite: Animals / Humans Idioma: En Ano de publicação: 2019 Tipo de documento: Article