Comparative genomics reveals a lack of evidence for pigeons as a main source of stx<sub>2f</sub>-carrying Escherichia coli causing disease in humans and the common existence of hybrid Shiga toxin-producing and enteropathogenic E. coli pathotypes.

van Hoek, Angela H A M; van Veldhuizen, Janieke N J; Friesema, Ingrid; Coipan, Claudia; Rossen, John W A; Bergval, Indra L; Franz, Eelco

Comparative genomics reveals a lack of evidence for pigeons as a main source of stx_2f-carrying Escherichia coli causing disease in humans and the common existence of hybrid Shiga toxin-producing and enteropathogenic E. coli pathotypes.

van Hoek, Angela H A M; van Veldhuizen, Janieke N J; Friesema, Ingrid; Coipan, Claudia; Rossen, John W A; Bergval, Indra L; Franz, Eelco.

Afiliação

van Hoek AHAM; Centre for Infectious Disease Control (CIb), National Institute for Public Health and the Environment (RIVM), Bilthoven, the Netherlands. angela.van.hoek@rivm.nl.
van Veldhuizen JNJ; Centre for Infectious Disease Control (CIb), National Institute for Public Health and the Environment (RIVM), Bilthoven, the Netherlands.
Friesema I; Centre for Infectious Disease Control (CIb), National Institute for Public Health and the Environment (RIVM), Bilthoven, the Netherlands.
Coipan C; Centre for Infectious Disease Control (CIb), National Institute for Public Health and the Environment (RIVM), Bilthoven, the Netherlands.
Rossen JWA; Department of Medical Microbiology and Infection Prevention, University of Groningen, University Medical Center Groningen, Groningen, the Netherlands.
Bergval IL; Centre for Infectious Disease Control (CIb), National Institute for Public Health and the Environment (RIVM), Bilthoven, the Netherlands.
Franz E; Centre for Infectious Disease Control (CIb), National Institute for Public Health and the Environment (RIVM), Bilthoven, the Netherlands.

BMC Genomics ; 20(1): 271, 2019 Apr 05.

Article em En | MEDLINE | ID: mdl-30953471

Assuntos

Doenças das Aves/epidemiologia; Escherichia coli Enteropatogênica/patogenicidade; Infecções por Escherichia coli/epidemiologia; Proteínas de Escherichia coli/metabolismo; Genômica/métodos; Toxina Shiga/metabolismo; Fatores de Virulência/metabolismo; Animais; Columbidae; Escherichia coli Enteropatogênica/classificação; Infecções por Escherichia coli/metabolismo; Infecções por Escherichia coli/microbiologia; Proteínas de Escherichia coli/genética; Genoma Bacteriano; Humanos; Filogenia; Toxina Shiga/genética; Fatores de Virulência/genética

Palavras-chave

Clonal lineages; Comparative genomics; Human; Hybrid pathotypes; Pathogens; Pigeon; Reservoir; STEC; Stx2f; tEPEC

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Doenças das Aves / Toxina Shiga / Genômica / Proteínas de Escherichia coli / Fatores de Virulência / Infecções por Escherichia coli / Escherichia coli Enteropatogênica Tipo de estudo: Prognostic_studies Limite: Animals / Humans Idioma: En Ano de publicação: 2019 Tipo de documento: Article

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