A mitochondria targeting artesunate prodrug-loaded nanoparticle exerting anticancer activity via iron-mediated generation of the reactive oxygen species.
Chem Commun (Camb)
; 55(33): 4781-4784, 2019 Apr 18.
Article
em En
| MEDLINE
| ID: mdl-30957121
ABSTRACT
An artesunate anticancer prodrug with a long aliphatic chain N,N'-bis(dodecyl)-l-glutamic diamide was developed into nanoparticle via iron-mediated ROS generation.
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Pró-Fármacos
/
Espécies Reativas de Oxigênio
/
Artesunato
/
Ferro
/
Mitocôndrias
/
Antineoplásicos
Idioma:
En
Ano de publicação:
2019
Tipo de documento:
Article