A Pediatric Case of Transformed Mycosis Fungoides in a BRCA2 Positive Patient.
J Pediatr Hematol Oncol
; 42(5): e361-e364, 2020 07.
Article
em En
| MEDLINE
| ID: mdl-30969264
ABSTRACT
Cutaneous T-cell lymphomas are very rare in children. Although mycosis fungoides is the most common of these rare cutaneous T-cell lymphomas in children, transformation to an aggressive malignancy remains extremely uncommon, and there are no clear guidelines for clinical management in the pediatric population. In addition, the increased usage of next-generation sequencing for pediatric patients with unusual malignancies may result in the discovery of pathogenic germline mutations, though the association between these mutations and the patient's cancer is not always clear. We present here a unique pediatric case of transformed mycosis fungoides in a patient with BRCA2 mutation.
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Neoplasias Cutâneas
/
Linfoma Cutâneo de Células T
/
Micose Fungoide
/
Proteína BRCA2
/
Mutação
Tipo de estudo:
Guideline
/
Prognostic_studies
Limite:
Child, preschool
/
Female
/
Humans
Idioma:
En
Ano de publicação:
2020
Tipo de documento:
Article