Atomic Mechanisms of Timothy Syndrome-Associated Mutations in Calcium Channel Cav1.2.

Korkosh, Vyacheslav S; Kiselev, Artem M; Mikhaylov, Evgeny N; Kostareva, Anna A; Zhorov, Boris S

Korkosh, Vyacheslav S; Kiselev, Artem M; Mikhaylov, Evgeny N; Kostareva, Anna A; Zhorov, Boris S.

Afiliação

Korkosh VS; Almazov National Medical Research Centre, Saint Petersburg, Russia.
Kiselev AM; I. M. Sechenov Institute of Evolutionary Physiology and Biochemistry, Russian Academy of Sciences, Saint Petersburg, Russia.
Mikhaylov EN; Almazov National Medical Research Centre, Saint Petersburg, Russia.
Kostareva AA; Almazov National Medical Research Centre, Saint Petersburg, Russia.
Zhorov BS; Almazov National Medical Research Centre, Saint Petersburg, Russia.

Front Physiol ; 10: 335, 2019.

Article em En | MEDLINE | ID: mdl-30984024

Palavras-chave

LQTS; Monte Carlo energy minimizations; cardiac arrhythmias; channel gating; channelopathies; homology modeling; state-dependent contacts; voltage-dependent inactivation

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Texto completo: 1 Base de dados: MEDLINE Tipo de estudo: Risk_factors_studies Idioma: En Ano de publicação: 2019 Tipo de documento: Article

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Texto completo: 1 Base de dados: MEDLINE Tipo de estudo: Risk_factors_studies Idioma: En Ano de publicação: 2019 Tipo de documento: Article