Improved outcomes with surgery compared to radiofrequency ablation in the treatment of resectable hepatocellular carcinoma.
Eur J Gastroenterol Hepatol
; 31(11): 1397-1402, 2019 Nov.
Article
em En
| MEDLINE
| ID: mdl-30985455
ABSTRACT
BACKGROUND:
While overall cancer incidence and mortality have decreased over the last decade, hepatocellular carcinoma (HCC) cases have increased sharply.OBJECTIVE:
This study set out to evaluate the utility of surgery for resectable single tumor HCC in this setting. PATIENTS ANDMETHODS:
This study analyzed the National Cancer Database, selecting all patients with a histological diagnosis of HCC and an isolated tumor (≤5 cm) treated with radiofrequency ablation (RFA) or surgical resection.RESULTS:
A total of 7821 patients were identified for this study. In the patients with a single tumor up to 3 cm, 40% had a surgical resection and 60% had RFA. In the group with a tumor 3.01-5 cm, 62% had a surgical resection and 38% had RFA. Patients with a single tumor up to 5 cm had a 3-year survival of 60% after resection compared to 42% with RFA. When the patients were split into those with a tumor up to 3 cm or a tumor 3.01-5 cm, there was a survival benefit in the surgical resection cohort.CONCLUSION:
Surgical resection may be underutilized in the USA for resectable HCC, especially in patients with a tumor up to 3 cm.
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Ablação por Cateter
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Carcinoma Hepatocelular
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Hepatectomia
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Neoplasias Hepáticas
Limite:
Aged
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Aged80
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Female
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Humans
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Male
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Middle aged
Idioma:
En
Ano de publicação:
2019
Tipo de documento:
Article