Comparing the Utility of Mitochondrial and Nuclear DNA to Adjust for Genetic Ancestry in Association Studies.

Miller, Brendan; Arpawong, Thalida E; Jiao, Henry; Kim, Su-Jeong; Yen, Kelvin; Mehta, Hemal H; Wan, Junxiang; Carpten, John C; Cohen, Pinchas

Miller, Brendan; Arpawong, Thalida E; Jiao, Henry; Kim, Su-Jeong; Yen, Kelvin; Mehta, Hemal H; Wan, Junxiang; Carpten, John C; Cohen, Pinchas.

Afiliação

Miller B; Leonard Davis School of Gerontology, University of Southern California, Los Angeles, CA 90089, USA. brendajm@usc.edu.
Arpawong TE; Leonard Davis School of Gerontology, University of Southern California, Los Angeles, CA 90089, USA. arpawong@usc.edu.
Jiao H; Leonard Davis School of Gerontology, University of Southern California, Los Angeles, CA 90089, USA. henrygji@usc.edu.
Kim SJ; Leonard Davis School of Gerontology, University of Southern California, Los Angeles, CA 90089, USA. sujkim@usc.edu.
Yen K; Leonard Davis School of Gerontology, University of Southern California, Los Angeles, CA 90089, USA. kelviny@usc.edu.
Mehta HH; Leonard Davis School of Gerontology, University of Southern California, Los Angeles, CA 90089, USA. hemalmeh@usc.edu.
Wan J; Leonard Davis School of Gerontology, University of Southern California, Los Angeles, CA 90089, USA. junxianw@usc.edu.
Carpten JC; Department of Translational Genomics and Institute for Translational Genomics, Keck School of Medicine of the University of Southern California, Los Angeles, CA 90033, USA. carpten@usc.edu.
Cohen P; Leonard Davis School of Gerontology, University of Southern California, Los Angeles, CA 90089, USA. hassy@usc.edu.

Cells ; 8(4)2019 04 03.

Article em En | MEDLINE | ID: mdl-30987182

Assuntos

Núcleo Celular/genética; DNA Mitocondrial/genética; Genética Populacional; Estudo de Associação Genômica Ampla; Etnicidade/genética; Humanos; Polimorfismo de Nucleotídeo Único/genética; Análise de Componente Principal

Palavras-chave

DNA; genetics; genome-wide association study; mitochondrial; polymorphism; population; principal component analysis; single nucleotide

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: DNA Mitocondrial / Núcleo Celular / Estudo de Associação Genômica Ampla / Genética Populacional Tipo de estudo: Risk_factors_studies Limite: Humans Idioma: En Ano de publicação: 2019 Tipo de documento: Article

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