Your browser doesn't support javascript.
loading
Partially methylated domains are hypervariable in breast cancer and fuel widespread CpG island hypermethylation.
Brinkman, Arie B; Nik-Zainal, Serena; Simmer, Femke; Rodríguez-González, F Germán; Smid, Marcel; Alexandrov, Ludmil B; Butler, Adam; Martin, Sancha; Davies, Helen; Glodzik, Dominik; Zou, Xueqing; Ramakrishna, Manasa; Staaf, Johan; Ringnér, Markus; Sieuwerts, Anieta; Ferrari, Anthony; Morganella, Sandro; Fleischer, Thomas; Kristensen, Vessela; Gut, Marta; van de Vijver, Marc J; Børresen-Dale, Anne-Lise; Richardson, Andrea L; Thomas, Gilles; Gut, Ivo G; Martens, John W M; Foekens, John A; Stratton, Michael R; Stunnenberg, Hendrik G.
Afiliação
  • Brinkman AB; Department of Molecular Biology, Faculty of Science, Radboud Institute for Molecular Life Sciences, Radboud University, PO Box 9101, Nijmegen, 6500 HB, The Netherlands. a.brinkman@science.ru.nl.
  • Nik-Zainal S; Wellcome Trust Sanger Institute, Hinxton, Cambridge, CB10 1SA, UK.
  • Simmer F; Academic Department of Medical Genetics, University of Cambridge, Cambridge, CB2 0QQ, UK.
  • Rodríguez-González FG; Department of Molecular Biology, Faculty of Science, Radboud Institute for Molecular Life Sciences, Radboud University, PO Box 9101, Nijmegen, 6500 HB, The Netherlands.
  • Smid M; Department of Pathology, Radboud University Nijmegen Medical Centre, P.O. Box 9101, Nijmegen, 6500 HB, The Netherlands.
  • Alexandrov LB; Erasmus MC Cancer Institute and Cancer Genomics Netherlands, Department of Medical Oncology, Erasmus University Medical Center, Rotterdam, 3015 GD, The Netherlands.
  • Butler A; Erasmus MC Cancer Institute and Cancer Genomics Netherlands, Department of Medical Oncology, Erasmus University Medical Center, Rotterdam, 3015 GD, The Netherlands.
  • Martin S; Wellcome Trust Sanger Institute, Hinxton, Cambridge, CB10 1SA, UK.
  • Davies H; Theoretical Biology and Biophysics (T-6), Los Alamos National Laboratory, Los Alamos, NM, 87545, USA.
  • Glodzik D; Center for Nonlinear Studies, Los Alamos National Laboratory, Los Alamos, NM, 87545, USA.
  • Zou X; Wellcome Trust Sanger Institute, Hinxton, Cambridge, CB10 1SA, UK.
  • Ramakrishna M; Wellcome Trust Sanger Institute, Hinxton, Cambridge, CB10 1SA, UK.
  • Staaf J; Wellcome Trust Sanger Institute, Hinxton, Cambridge, CB10 1SA, UK.
  • Ringnér M; Wellcome Trust Sanger Institute, Hinxton, Cambridge, CB10 1SA, UK.
  • Sieuwerts A; Wellcome Trust Sanger Institute, Hinxton, Cambridge, CB10 1SA, UK.
  • Ferrari A; Wellcome Trust Sanger Institute, Hinxton, Cambridge, CB10 1SA, UK.
  • Morganella S; Division of Oncology and Pathology, Department of Clinical Sciences Lund, Lund University, Lund, SE-223 81, Sweden.
  • Fleischer T; Division of Oncology and Pathology, Department of Clinical Sciences Lund, Lund University, Lund, SE-223 81, Sweden.
  • Kristensen V; Erasmus MC Cancer Institute and Cancer Genomics Netherlands, Department of Medical Oncology, Erasmus University Medical Center, Rotterdam, 3015 GD, The Netherlands.
  • Gut M; Synergie Lyon Cancer, Centre Léon Bérard, 28 rue Laënnec, Lyon Cedex 08, France.
  • van de Vijver MJ; European Molecular Biology Laboratory, European Bioinformatics Institute, Wellcome Trust Genome Campus, Hinxton, Cambridgeshire, CB10 1SD, UK.
  • Børresen-Dale AL; Department of Genetics, Institute for Cancer Research, Oslo University Hospital, The Norwegian Radium Hospital, Oslo, 0310, Norway.
  • Richardson AL; Department of Genetics, Institute for Cancer Research, Oslo University Hospital, The Norwegian Radium Hospital, Oslo, 0310, Norway.
  • Thomas G; K.G. Jebsen Centre for Breast Cancer Research, Institute for Clinical Medicine, University of Oslo, Oslo, 0316, Norway.
  • Gut IG; Department of Clinical Molecular Biology and Laboratory Science (EpiGen), Division of Medicine, Akershus University Hospital, Lørenskog, 1478, Norway.
  • Martens JWM; Centro Nacional de Análisis Genómico (CNAG), Parc Científic de Barcelona, Barcelona, 08028, Spain.
  • Foekens JA; Department of Pathology, Academic Medical Center, Meibergdreef 9, Amsterdam, AZ 1105, The Netherlands.
  • Stratton MR; Department of Genetics, Institute for Cancer Research, Oslo University Hospital, The Norwegian Radium Hospital, Oslo, 0310, Norway.
  • Stunnenberg HG; K.G. Jebsen Centre for Breast Cancer Research, Institute for Clinical Medicine, University of Oslo, Oslo, 0316, Norway.
Nat Commun ; 10(1): 1749, 2019 04 15.
Article em En | MEDLINE | ID: mdl-30988298
Assuntos
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Neoplasias da Mama / Ilhas de CpG Tipo de estudo: Risk_factors_studies Limite: Female / Humans Idioma: En Ano de publicação: 2019 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Neoplasias da Mama / Ilhas de CpG Tipo de estudo: Risk_factors_studies Limite: Female / Humans Idioma: En Ano de publicação: 2019 Tipo de documento: Article