[Oesophagus polyps: Giant fibrovascular polyp of the oesophagus disappears!] / Polypes Åsophagiens : le polype géant fibrovasculaire de l'Åsophage n'existe plus !
Ann Pathol
; 39(3): 221-226, 2019 Jun.
Article
em Fr
| MEDLINE
| ID: mdl-31003707
ABSTRACT
The giant fibrovascular polyp of the esophagus is a rare, benign and typical entity described in 1957. This lesion is easily identifiable in its macroscopic and microscopic aspects. However, recent studies question the existence of the giant fibrovascular polyp of the esophagus. The demonstration of an amplification of the MDM2 gene poses the diagnosis of well-differentiated liposarcoma. We describe here a case of an esophagus polyp in a 67-year-old man. The diagnosis of giant fibrovascular polyp of the esophagus was initially retained. Secondly, the immunohistochemical and fluorescence in situ hybridization techniques showed amplification of the MDM2 gene and reclassified the lesion to a well-differentiated liposarcoma. The search for an undifferentiated contingent is essential to not ignore a dedifferentiated liposarcoma, which is a high-grade sarcoma with a poorer prognosis.
Palavras-chave
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Pólipos
/
Neoplasias Esofágicas
/
Proteínas Proto-Oncogênicas c-mdm2
/
Lipossarcoma
Tipo de estudo:
Diagnostic_studies
/
Prognostic_studies
Limite:
Aged
/
Humans
/
Male
Idioma:
Fr
Ano de publicação:
2019
Tipo de documento:
Article