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Fully Three-Dimensional Bioprinted Skin Equivalent Constructs with Validated Morphology and Barrier Function.
Derr, Kristy; Zou, Jinyun; Luo, Keren; Song, Min Jae; Sittampalam, G Sitta; Zhou, Chao; Michael, Sam; Ferrer, Marc; Derr, Paige.
Afiliação
  • Derr K; 1 Department of Preclinical Innovation, National Center for Advancing Translational Sciences, National Institutes of Health, Rockville, Maryland.
  • Zou J; 2 Department of Electrical and Computer Engineering, Bethlehem, Pennsylvania.
  • Luo K; 2 Department of Electrical and Computer Engineering, Bethlehem, Pennsylvania.
  • Song MJ; 3 National Eye Institute, National Institutes of Health, Rockville, Maryland.
  • Sittampalam GS; 1 Department of Preclinical Innovation, National Center for Advancing Translational Sciences, National Institutes of Health, Rockville, Maryland.
  • Zhou C; 2 Department of Electrical and Computer Engineering, Bethlehem, Pennsylvania.
  • Michael S; 4 Department of Bioengineering, Lehigh University, Bethlehem, Pennsylvania.
  • Ferrer M; 1 Department of Preclinical Innovation, National Center for Advancing Translational Sciences, National Institutes of Health, Rockville, Maryland.
  • Derr P; 1 Department of Preclinical Innovation, National Center for Advancing Translational Sciences, National Institutes of Health, Rockville, Maryland.
Tissue Eng Part C Methods ; 25(6): 334-343, 2019 06.
Article em En | MEDLINE | ID: mdl-31007132
ABSTRACT
IMPACT STATEMENT This article describes a method for the biofabrication of skin tissue equivalents in a multiwell plate format. The technique and results overcome shortcomings of previously published engineering methods, and show good architecture and barrier function from well to well; thus it may be used for compound functional testing and for the development of disease tissue models for screening.
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Pele Artificial / Alicerces Teciduais / Bioimpressão / Impressão Tridimensional Tipo de estudo: Prognostic_studies Limite: Humans Idioma: En Ano de publicação: 2019 Tipo de documento: Article

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Pele Artificial / Alicerces Teciduais / Bioimpressão / Impressão Tridimensional Tipo de estudo: Prognostic_studies Limite: Humans Idioma: En Ano de publicação: 2019 Tipo de documento: Article