A compendium on single-cell analysis for the curious.

ABSTRACT

Single-cell analysis is impacting biology and medicine by changing the scale and resolution at which we investigate multicellular organisms. A particular, overarching aim of this field is to characterize the programmed development of all different cell types in the human body, as well as their individual spatial, molecular, and functional characteristics. This vast research program is generating a much-needed source of fundamental biological insights that will provide a basis for new diagnostic and therapeutic approaches. With this Focus Issue on Single-Cell Analyses, The FEBS Journal offers interested readers an excellent introduction to this exciting research field, including ideas on how a wide community can benefit from the powerful approaches and technologies as well as the biological knowledge generated.