Selective effect of lithium on cognitive performance in man.
Psychopharmacology (Berl)
; 91(1): 109-11, 1987.
Article
em En
| MEDLINE
| ID: mdl-3103153
The effects of lithium on psychomotor performance were examined in six healthy male volunteers (aged 26-31 years) and compared with those of a similar control population. Three computerised psychomotor tests (serial reaction time, semantic reasoning and syntatic reasoning) were administered before lithium, after 5 and 22 days of lithium carbonate (800 mg/d) and 4 days and 1 month after stopping the lithium. The only significant effect was an impairment of semantic reasoning during the chronic (22 day) test. This suggests a selective effect of lithium on associative mental tasks and may explain the subjects' experience of slowing in recall of object names whilst taking lithium.
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Base de dados:
MEDLINE
Assunto principal:
Cognição
/
Lítio
Limite:
Adult
/
Humans
/
Male
Idioma:
En
Ano de publicação:
1987
Tipo de documento:
Article