Dopamine dysregulation syndrome in non-Parkinson's disease patients: a systematic review.
Australas Psychiatry
; 27(5): 456-461, 2019 Oct.
Article
em En
| MEDLINE
| ID: mdl-31032624
ABSTRACT
OBJECTIVES:
To explore the presence of dopamine dysregulation syndrome in non-Parkinson's disease patients receiving dopamine replacement therapy.METHODS:
Electronic searches were conducted of Medline, Embase, PsycINFO and PreMedline to capture articles related to dopamine misuse or factitious disorder combined with the presence of dopamine replacement therapy or a non-Parkinson's disease population. In total, 430 articles were reviewed and studies that addressed dopamine dysregulation syndrome in non-Parkinson's disease patients were included.RESULTS:
Nine case reports were identified.CONCLUSIONS:
The pathophysiology underlying dopamine dysregulation syndrome has been thoroughly explored with numerous mechanisms posited. What remains unclear is whether dopamine dysregulation syndrome is a phenomenon specific to Parkinson's disease, as indicated in the proposed diagnostic criteria. A more useful predictor of susceptibility to dopamine dysregulation syndrome may be temperamental traits such as novelty seeking and impulsivity, which overlap with predisposing factors for an addiction disorder.Palavras-chave
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Temperamento
/
Dopaminérgicos
/
Dopamina
/
Comportamento Aditivo
/
Transtornos Autoinduzidos
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Uso Indevido de Medicamentos
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Transtornos Disruptivos, de Controle do Impulso e da Conduta
Tipo de estudo:
Prognostic_studies
/
Systematic_reviews
Limite:
Humans
Idioma:
En
Ano de publicação:
2019
Tipo de documento:
Article