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Modified U1 snRNA and antisense oligonucleotides rescue splice mutations in SLC26A4 that cause hereditary hearing loss.
Lee, Byeonghyeon; Kim, Ye-Ri; Kim, Sang-Joo; Goh, Sung-Ho; Kim, Jong-Heun; Oh, Se-Kyung; Baek, Jeong-In; Kim, Un-Kyung; Lee, Kyu-Yup.
Afiliação
  • Lee B; Department of Biology, College of Natural Sciences, Kyungpook National University, Daegu, Republic of Korea.
  • Kim YR; BK21 Plus KNU Creative BioResearch Group, School of Life Sciences, Kyungpook National University, Daegu, Republic of Korea.
  • Kim SJ; Department of Biology, College of Natural Sciences, Kyungpook National University, Daegu, Republic of Korea.
  • Goh SH; BK21 Plus KNU Creative BioResearch Group, School of Life Sciences, Kyungpook National University, Daegu, Republic of Korea.
  • Kim JH; Department of Biology, College of Natural Sciences, Kyungpook National University, Daegu, Republic of Korea.
  • Oh SK; BK21 Plus KNU Creative BioResearch Group, School of Life Sciences, Kyungpook National University, Daegu, Republic of Korea.
  • Baek JI; Therapeutic Target Discovery Branch, National Cancer Center, Goyang-si, Gyeonggi-do, Republic of Korea.
  • Kim UK; Department of Biology, College of Natural Sciences, Kyungpook National University, Daegu, Republic of Korea.
  • Lee KY; BK21 Plus KNU Creative BioResearch Group, School of Life Sciences, Kyungpook National University, Daegu, Republic of Korea.
Hum Mutat ; 40(8): 1172-1180, 2019 08.
Article em En | MEDLINE | ID: mdl-31033086
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: RNA Nuclear Pequeno / Oligonucleotídeos Antissenso / Transportadores de Sulfato / Perda Auditiva Neurossensorial Limite: Humans Idioma: En Ano de publicação: 2019 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: RNA Nuclear Pequeno / Oligonucleotídeos Antissenso / Transportadores de Sulfato / Perda Auditiva Neurossensorial Limite: Humans Idioma: En Ano de publicação: 2019 Tipo de documento: Article