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AMPK activation induced in pemetrexed-treated cells is associated with development of drug resistance independently of target enzyme expression.
Qin, Yiyang; Sekine, Ikuo; Hanazono, Michiko; Morinaga, Takao; Fan, Mengmeng; Takiguchi, Yuichi; Tada, Yuji; Shingyoji, Masato; Yamaguchi, Naoto; Tagawa, Masatoshi.
Afiliação
  • Qin Y; Division of Pathology and Cell Therapy, Chiba Cancer Center Research Institute, Japan.
  • Sekine I; Laboratory of Molecular Cell Biology, Graduate School of Pharmaceutical Sciences, Chiba University, Japan.
  • Hanazono M; Department of Medical Oncology, Faculty of Medicine, University of Tsukuba, Japan.
  • Morinaga T; Division of Pathology and Cell Therapy, Chiba Cancer Center Research Institute, Japan.
  • Fan M; Department of Respirology, Graduate School of Medicine, Chiba University, Japan.
  • Takiguchi Y; Division of Pathology and Cell Therapy, Chiba Cancer Center Research Institute, Japan.
  • Tada Y; Department of Medical Oncology, Graduate School of Medicine, Chiba University, Japan.
  • Shingyoji M; Department of Medical Oncology, Graduate School of Medicine, Chiba University, Japan.
  • Yamaguchi N; Department of Respirology, Graduate School of Medicine, Chiba University, Japan.
  • Tagawa M; Division of Respirology, Chiba Cancer Center, Japan.
Mol Oncol ; 13(6): 1419-1432, 2019 06.
Article em En | MEDLINE | ID: mdl-31033201

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Sobrevivência Celular / Proteínas Quinases Ativadas por AMP / Pemetrexede / Mesotelioma Tipo de estudo: Risk_factors_studies Limite: Humans Idioma: En Ano de publicação: 2019 Tipo de documento: Article

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Sobrevivência Celular / Proteínas Quinases Ativadas por AMP / Pemetrexede / Mesotelioma Tipo de estudo: Risk_factors_studies Limite: Humans Idioma: En Ano de publicação: 2019 Tipo de documento: Article