[A case of chordoma presenting as recurrent bacterial meningitis with cerebrospinal fluid leakage].
Rinsho Shinkeigaku
; 59(5): 264-267, 2019 May 28.
Article
em Ja
| MEDLINE
| ID: mdl-31061304
ABSTRACT
A 52-year-old man was admitted to our hospital because of two episodes of bacterial meningitis within a 6-month period. CSF examination showed neutrophilic pleocytosis with marked elevation of protein and hypoglycorrhachia, but the inflammatory reaction was mild and blood and CSF cultures were negative. At the time of the second admission, intermittent watery nasal discharge caused by CSF rhinorrhea was evident. CT and MR imaging revealed a tiny clival bone defect, and transnasal endoscopic repair was performed successfully. The pathological diagnosis was chordoma based on immunohistochemical staining for brachyury. Although chordoma presenting as recurrent bacterial meningitis occurs extremely rare, asking patients detailed questions about the CSF rhinorrhea must be essential for disclosing unclear infection sources.
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Base de dados:
MEDLINE
Assunto principal:
Cordoma
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Rinorreia de Líquido Cefalorraquidiano
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Meningites Bacterianas
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Neoplasias da Base do Crânio
Limite:
Humans
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Male
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Middle aged
Idioma:
Ja
Ano de publicação:
2019
Tipo de documento:
Article