Platelet glycoprotein VI genetic quantitative and qualitative defects.
Platelets
; 30(6): 708-713, 2019.
Article
em En
| MEDLINE
| ID: mdl-31068042
ABSTRACT
Platelet membrane glycoprotein VI (GPVI) is increasingly recognized as an important receptor for thrombus formation and growth. Numerous arguments have been published indicating that GPVI plays a major role in thrombosis without being essential for physiological hemostasis. In humans, GPVI deficiencies are rarely reported. These are most often deficiencies occurring in the context of autoimmunity and, more rarely, genetic deficits. The purpose of this review is to compile data on the quantitative and qualitative genetic abnormalities of GPVI.
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Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Plaquetas
/
Glicoproteínas da Membrana de Plaquetas
Tipo de estudo:
Qualitative_research
Limite:
Humans
Idioma:
En
Ano de publicação:
2019
Tipo de documento:
Article