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Evolving Roles of Fluorodeoxyglucose and Sodium Fluoride in Assessment of Multiple Myeloma Patients: Introducing a Novel Method of PET Quantification to Overcome Shortcomings of the Existing Approaches.
Zadeh, Mahdi Zirakchian; Raynor, William Y; Seraj, Siavash Mehdizadeh; Ayubcha, Cyrus; Kothekar, Esha; Werner, Thomas; Alavi, Abass.
Afiliação
  • Zadeh MZ; Department of Radiology, University of Pennsylvania, 3400 Spruce Street, Philadelphia, PA 19104, USA; Department of Radiology, Children's Hospital of Philadelphia, 3401 Civic Center Boulevard, Philadelphia, PA 19104, USA.
  • Raynor WY; Department of Radiology, University of Pennsylvania, 3400 Spruce Street, Philadelphia, PA 19104, USA; Drexel University College of Medicine, 2900 West Queen Lane, Philadelphia, PA 19129, USA.
  • Seraj SM; Department of Radiology, University of Pennsylvania, 3400 Spruce Street, Philadelphia, PA 19104, USA.
  • Ayubcha C; Department of Radiology, University of Pennsylvania, 3400 Spruce Street, Philadelphia, PA 19104, USA.
  • Kothekar E; Department of Radiology, University of Pennsylvania, 3400 Spruce Street, Philadelphia, PA 19104, USA.
  • Werner T; Department of Radiology, University of Pennsylvania, 3400 Spruce Street, Philadelphia, PA 19104, USA.
  • Alavi A; Department of Radiology, University of Pennsylvania, 3400 Spruce Street, Philadelphia, PA 19104, USA. Electronic address: abass.alavi@uphs.upenn.edu.
PET Clin ; 14(3): 341-352, 2019 Jul.
Article em En | MEDLINE | ID: mdl-31084774
ABSTRACT
PET with fluorodeoxyglucose and sodium fluoride (NaF) radiotracers has shown a great promise in assessing patients with multiple myeloma (MM). However, the standardization of PET/computed tomography scans interpretation in patients with myeloma in clinical practice is still debatable. This article reviews available data regarding the use of fluorodeoxyglucose and NaF PET in patients with MM. Introduced is a novel method of PET quantification as applied to patients with MM. A new concept for PET-based evaluation of patients with MM is also discussed dual time point imaging. Finally, the role of NaF in assessment of cardiovascular complications of MM is described.
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Fluoreto de Sódio / Compostos Radiofarmacêuticos / Fluordesoxiglucose F18 / Tomografia por Emissão de Pósitrons combinada à Tomografia Computadorizada / Mieloma Múltiplo Limite: Humans Idioma: En Ano de publicação: 2019 Tipo de documento: Article
Texto completo
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Fluoreto de Sódio / Compostos Radiofarmacêuticos / Fluordesoxiglucose F18 / Tomografia por Emissão de Pósitrons combinada à Tomografia Computadorizada / Mieloma Múltiplo Limite: Humans Idioma: En Ano de publicação: 2019 Tipo de documento: Article